ArticleJMIR research protocols2026
Effectiveness of Multisensory Stimulation on Cognitive Function in Older Adults With Mild Cognitive Impairment: Protocol for a Systematic Review.
Article in JMIR research protocols, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Effectiveness of Multisensory Stimulation on Cognitive Function in Older Adults With Mild Cognitive Impairment: Protocol for a Systematic Review.JMIR research protocols · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Mild cognitive impairment (MCI) is an intermediate state between normal cognitive aging and dementia, with a global geriatric prevalence of 23.7%. Multisensory stimulation (MSS) has emerged as a promising approach to improve cognitive impairment. However, relevant research is heterogeneous, and the evidence has not yet been systematically synthesized. Objective: This study aims to systematically review the evidence on the effectiveness of MSS on cognitive function in older adults with MCI, appraise different MSS interventions, identify limitations in study design and implementation, and provide recommendations for future trials. Methods: A comprehensive search will be conducted in PubMed, Embase, PsycInfo, Web of Science Core Collection, and the Cochrane Library, with manual screening of reference lists and gray literature. Eligible studies are randomized controlled trials that involve adults aged 60 years or older with confirmed MCI and evaluate intentional MSS with reported parameters. Two reviewers will independently select the studies, extract the data, and assess risk of bias using version 2 of the Cochrane risk-of-bias tool for randomized trials. The primary outcomes are global cognitive function, memory, executive function, and attention; secondary outcomes include quality of life, adherence, and safety. A meta-analysis will be performed using mean differences or standardized mean differences if the studies are sufficiently comparable in population, interventions, and outcomes; otherwise, a narrative synthesis will be conducted. Results: This protocol has been registered in PROSPERO, and the methodological frameworks were finalized on October 5, 2025. The systematic literature search was completed between November 1, 2025, and December 31, 2025, followed by study screening and data extraction between January 1, 2026, and February 28, 2026. Data synthesis and final manuscript preparation are expected to be completed by April 30, 2026. Conclusions: The systematic review is expected to provide a comprehensive synthesis of the evidence on MSS for older adults with MCI and will help identify the optimal intervention parameters and implementation strategies. The findings may help inform future trial design and the optimization of nonpharmacological interventions for cognitive health in older adults with MCI.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.