ArticleProceedings of the National Academy of Sciences of the United States of America2026
NAT10/ac
Yunkun Lu, Kainan Lin, Qianqian Wang, Xiang Huang, Lianyu Lin, Jie Dou, Yajuan Jiao, Yali Wang, Peng Xiao, Hongjun Chen and 4 more
Abstract read
In one paragraphArticle in Proceedings of the National Academy of Sciences of the United States of America, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
14 authors.
Yunkun Lu *Department of General Surgery, Sir Run-Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou 310016, China.ORCID 0000-0001-7605-1259 Kainan Lin *Department of General Surgery, Sir Run-Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou 310016, China.ORCID 0009-0009-0124-1379 Qianqian Wang *Department of General Surgery, Sir Run-Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou 310016, China.
Xiang HuangDepartment of General Surgery, Sir Run-Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou 310016, China.
Lianyu LinCollege of Life Science, Fujian Agriculture and Forestry University, Fuzhou 350002, China.
Jie DouDepartment of General Surgery, Sir Run-Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou 310016, China.
Yajuan JiaoDepartment of Gastroenterology, Sir Run-Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou 310016, China.
Yali WangDepartment of General Surgery, Sir Run-Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou 310016, China.
Peng XiaoDepartment of Gastroenterology, Sir Run-Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou 310016, China.ORCID 0000-0003-0075-581X Hongjun ChenDepartment of General Surgery, Sir Run-Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou 310016, China.ORCID 0000-0002-0936-2599 Silin LiDepartment of General Surgery, Sir Run-Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou 310016, China.
Yangtao XueDepartment of General Surgery, Sir Run-Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou 310016, China.
Shunmin HeKey Laboratory of RNA Biology, Center for Big Data Research in Health, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.ORCID 0000-0002-7294-0865 Junjie XuDepartment of General Surgery, Sir Run-Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou 310016, China.ORCID 0000-0001-6507-6442 Funding
MOST | National Key Research and Development Program of China (NKPs) 2022YFC3400400MOST | National Natural Science Foundation of China (NSFC) 82403160MOST | NSFC | NSFC-Zhejiang Joint Fund | | Natural Science Foundation of Zhejiang Province (ZJNSF) LQN25H160023Zhejiang Provincial Natural Science Foundation of China LZ25H160001
6 · The paper itselfAbstract
Intrahepatic cholangiocarcinoma (ICC) poses a significant clinical challenge due to its insidious onset, aggressive biological behavior, and propensity for early metastasis, contributing to a dismal 5-y survival rate of less than 10%. Despite advances in understanding the dynamic changes in gene regulatory networks and chromatin landscapes during tumorigenesis, the functional interplay between RNA epitranscriptomic modifications and nuclear events in ICC remains poorly elucidated. Here, we identify
Indexed as
Bile Duct NeoplasmsCholangiocarcinomaChromatin Assembly and DisassemblyDNA Transposable ElementsAnimalsCell Line, TumorChromatin Assembly Factor-1Epigenesis, GeneticEpitranscriptomeGene Expression Regulation, NeoplasticHumansMiceCHAF1A protein, humanChromatin Assembly Factor-1DNA Transposable Elementsac4CCHAF1Achromatin remodelingintrahepatic cholangiocarcinomaNAT10
Identifiers
PMID42133812
PMCPMC13187814
What OpenQuestion holds
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