ReviewFEMS microbiology reviews2026
Mechanisms of chromosomal DNA replication in Escherichia coli and Bacillus subtilis.
Review in FEMS microbiology reviews, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Genetic dissection of DNA damage tolerance in Bacillus subtilis: RecA and recombination functions regulate translesion synthesis.Nucleic acids research · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Faithful DNA replication, which is a highly orchestrated process, is essential in all living organisms to ensure accurate transmission of genetic information to their descendants. In this review, we summarize the molecular mechanisms and dynamics of DNA replication in Escherichia coli and compare them with those of the phylogenetically distant Bacillus subtilis. Although the central features of replication initiation, elongation, termination, and restart are broadly conserved, distinct mechanisms have evolved to adapt each bacterium to its complex environment. This review highlights the players and outlines both the shared and divergent molecular mechanisms governing how the multi-component replication machines, the replisomes, are assembled at the origin of chromosomal replication, oriC, on a circular genome, undergo bidirectional replication elongation, and are ultimately disassembled upon reaching the terminus of replication, ter, region. In response to stress, (a) replication restart mechanism(s) operating at sites other than oriC re-assemble the replisome, allowing unidirectional DNA synthesis to resume, thereby ensuring completion of the cell cycle and maintenance of cell viability.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.