ArticleEchocardiography (Mount Kisco, N.Y.)2026
Color Doppler Ultrasound Parameters of Fetal Umbilical Artery and Middle Cerebral Artery Assist in Diagnosing Hypertensive Disorder of Pregnancy and Evaluating the Severity in Women of Advanced Maternal Age.
Article in Echocardiography (Mount Kisco, N.Y.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
objectiveThis study investigated the clinical significance of fetal umbilical artery (UA) and middle cerebral artery (MCA) Color Doppler parameters in the prenatal diagnosis of hypertensive disorder complicating pregnancy (HDCP) in pregnant women of advanced maternal age (AMA).
methodsAMA women with HDCP (245 gestational hypertension cases, 193 mild preeclampsia, 152 severe preeclampsia) and 80 healthy AMA pregnant women (control) in the late stage of singleton pregnancy were enrolled. Fetal UA and MCA Color Doppler parameters (systolic-to-diastolic ratio [S/D], pulsatility index [PI], and resistance index [RI]) were recorded. Influencing factors, and diagnostic and predictive value of these color Doppler parameters for HDCP and disease severity were assessed by logistic regression models and receiver operating characteristic curves.
resultsTotal bilirubin, total protein (TP), creatinine, Cl
conclusionThis study identifies several fetal UA and fetal MCA Color Doppler ultrasound parameters as potential influencing factors for HDCP occurrence and severity. The combined detection of these parameters may provide a reference for early recognizing HDCP and evaluating severity in women of AMA.
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