Evidence map›Paper›PMID 42133264›Full record

ArticleMagma (New York, N.Y.)2026

Reducing scan time burden for neonatal MRI of pulmonary structure using FLORET UTE.

Andrew D Hahn, Matt M Willmering, Nara S Higano, Conner J Wharff, Robert J Fleck, Robert P Guillerman, Jason S Woods, Sean B Fain

Abstract read
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In one paragraph

Article in Magma (New York, N.Y.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Andrew D HahnDepartment of Radiology, University of Iowa, Iowa City, IA, USA.
Matt M WillmeringCenter for Pulmonary Imaging Research, Division of Pulmonary Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
Nara S HiganoCenter for Pulmonary Imaging Research, Division of Pulmonary Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
Conner J WharffDepartment of Radiology, University of Iowa, Iowa City, IA, USA.
Robert J FleckDepartment of Pediatrics, University of Cincinnati, Cincinnati, OH, USA.
Robert P GuillermanDepartment of Radiology, Cincinnati Children's Hospital, Cincinnati, OH, USA.
Jason S WoodsCenter for Pulmonary Imaging Research, Division of Pulmonary Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
Sean B FainDepartment of Radiology, University of Iowa, Iowa City, IA, USA. sean-fain@uiowa.edu.ORCID http://orcid.org/0000-0001-5461-0646

Funding

Using MRI To Visualize Regional Therapy Response In Idiopathic Pulmonary FibrosisR01HL126771 · NHLBI · DUKE UNIVERSITY · PI Bastiaan Driehuys · 2015 to 2026
$6.6M
MRI Phenotyping of Severe BPD and Prediction of OutcomesR01HL146689 · NHLBI · CINCINNATI CHILDRENS HOSP MED CTR · PI JASON C WOODS · 2019 to 2026
$4.6M
Dynamic Imaging of Lung Ventilation and Perfusion Using CT and MRIR01HL169765 · NHLBI · UNIVERSITY OF IOWA · PI Sean Bedilion Fain · 2023 to 2026
$2.9M
NHLBI NIH HHS R01 HL126771NHLBI NIH HHS R01 HL146689NHLBI NIH HHS R01 HL169765
6 · The paper itself

Abstract

objectivePulmonary MRI in neonates can be performed with quality comparable to radial 3D ultrashort echo time (UTE) MRI in significantly less time using a FLORET trajectory. MATERIALS AND

methodsEighteen NICU patients with severe bronchopulmonary dysplasia (BPD), age 40.9 ± 3.0 weeks at time of imaging, underwent MRI using Radial and FLORET UTE at 1.5 T. Pulmonary signal-to-noise ratio (SNR), lung density, and radiologist scoring of motion artifacts and image quality were compared across sequence types.

resultsFLORET UTE reduced scan time by ~ 75% (4:40 vs. 16:41 min.) while incurring only ~ 10-30% SNR reduction vs. radial (radial vs. 1-hub FLORET: 9.8 ± 2.8 vs. 9.0 ± 2.6, radial vs. 3-hub FLORET: 9.2 ± 3.0 vs. 7.7 ± 2.3), P < 0.05. Normalized lung density measurements were elevated in FLORET (radial vs. 1-hub FLORET: 0.42 ± 0.13 vs. 0.49 ± 0.14, radial vs. 3-hub FLORET: 0.49 ± 0.13 vs. 0.51 ± 0.13), P < 0.05. Accounting for scan time differences, normalized radial SNR was 19% and 16% lower than 1-hub and 3-hub FLORET, respectively (P < 0.05). No significant differences in radiologist scores were found.

conclusionFLORET UTE images are of quality comparable to radial UTE at 75% of the total scan time, the current state of the art, and have a much greater time-SNR efficiency with enormous benefit in the neonatal population.

Indexed as

FLORETLungNeonatal MRIUltrashort echo time

Identifiers

PMID42133264

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.