Evidence map›Paper›PMID 42133249›Full record

ReviewCurrent pain and headache reports2026

Current Research on the Diagnosis and Management of Persistent Post-Traumatic Headache.

Lester Maxwell A Gallivan, Joanne Kacperski

Abstract readReview
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In one paragraph

Review in Current pain and headache reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Lester Maxwell A GallivanDivision of Neurology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA. lester.gallivan@cchmc.org.
Joanne KacperskiDivision of Neurology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewHeadache is a common symptom in patients with concussion and mild traumatic brain injury. While many patients experience spontaneous resolution of symptoms following injury, a subset develop persistent post-traumatic headache, and evidence-based guidance for the management of this condition remains limited in current clinical practice. RECENT

findingsPersistent post-traumatic headache (PPTH) is likely underrecognized, with evidence suggesting that individuals with a prior history of headache disorders or previous concussion may be at increased risk. Scheduled analgesics in the first 72 hours following injury or utilizing infusions can help reduce symptom severity in the acute period following injury. Pharmacological studies are limited but suggest treating based on the headache phenotype. Anti-CGRP therapies have shown promise in a variety of chronic headache types including PPTH, and non-pharmacological interventions including introduction of early exercise programs, cognitive behavioral therapy, and biofeedback can improve long term patient outcomes. Although the available evidence is limited, current research supports phenotype-guided pharmacologic treatment alongside a multidisciplinary approach incorporating early exercise and cognitive behavioral therapy.

Indexed as

AnalgesicsPost-Traumatic HeadacheCombined Modality TherapyHumansAnalgesicsEarly exercisePersistent post-concussive symptomsPost-traumatic headache

Identifiers

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.