Evidence map›Paper›PMID 42133229›Full record

ArticleJournal of cancer education : the official journal of the American Association for Cancer Education2026

Knowledge Levels and Awareness of Stem Cell Donation Among First-Degree Relatives of Patients with Hematological Malignancies.

Nevin Alayvaz Aslan, Talha Kartal, Osman Sencer Ekiz, Berkay Şişman

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Article in Journal of cancer education : the official journal of the American Association for Cancer Education, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Nevin Alayvaz AslanDepartment of Hematology, Pamukkale University Faculty of Medicine, Pamukkale, Denizli, 20070, Turkey. nevina@pau.edu.tr.ORCID http://orcid.org/0000-0003-3292-8519
Talha KartalPamukkale University Faculty of Medicine, Denizli, Turkey.ORCID http://orcid.org/0009-0001-4127-4177
Osman Sencer EkizPamukkale University Faculty of Medicine, Denizli, Turkey.ORCID http://orcid.org/0009-0000-2743-6021
Berkay ŞişmanPamukkale University Faculty of Medicine, Denizli, Turkey.ORCID http://orcid.org/0009-0005-4890-7693

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hematopoietic stem cell transplantation is a crucial treatment for hematological malignancies. This study aimed to evaluate knowledge, attitudes, and consideration to donate stem cells among first-degree relatives of adult patients with hematological malignancies. This descriptive cross-sectional study included 149 first-degree relatives of patients with hematological malignancies. Data were collected through face-to-face interviews using a 22-item structured questionnaire that assessed demographic characteristics, knowledge levels, and attitudes toward stem cell donation. Regarding general awareness, only 19.5% (n = 29) of participants reported having detailed knowledge about the concept and meaning of stem cell donation, while 9.4% (n = 14) had no idea at all. Regarding the specific technical procedure, 34.9% (n = 52) reported being completely unaware of how it is performed, and only 16.8% (n = 25) had detailed knowledge. Notably, while 88.6% (n = 132) of participants expressed a desire for more information, 62.4% (n = 93) stated they had not previously considered becoming donors. Multivariable logistic regression analysis revealed that knowledge level regarding the concept and meaning of stem cell donation was the only independent factor significantly associated with the prior consideration of donation (p = 0.007). First-degree relatives of patients with hematological malignancies often possess insufficient knowledge and hold misconceptions regarding stem cell donation. Since higher knowledge levels are significantly associated with a greater likelihood of having considered donation, it is essential to implement structured awareness campaigns with simplified, targeted content to expand the donor pool.

Indexed as

AwarenessFirst-degree relativesHematological malignanciesKnowledgeStem cell donation

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.