ArticleObesity surgery2026
Marginal Ulcers After Roux-en-Y Gastric Bypass: Patterns of Care, Treatment, and Outcomes from a Tertiary Referral Center.
Article in Obesity surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMarginal ulcers (MU) represent a common and serious complication following Roux-en-Y gastric bypass (RYGB). While most MUs heal with conservative therapy, a subset requires endoscopic or surgical intervention. This study aims to characterize management trajectories and identify predictors of perforation.
methodsA retrospective review was performed to identify patients who underwent RYGB between 2008 and 2023 at a tertiary referral center and were subsequently diagnosed with MU. Baseline characteristics, management strategies, and clinical outcomes were collected. MU management was categorized as medical, endoscopic, or surgical. Continuous variables were summarized using medians with interquartile ranges (IQR), and categorical variables using frequencies and percentages. Univariate testing, multivariate regression, and time-to-event analyses were used to assess predictors of MU perforation.
resultsAmong 2106 patients, 241 patients developed MUs (incidence 11.4%). Ulcers were identified at a median of 7.1 months (IQR 3.0-16.2) following RYGB. Most patients (77.2%) resolved with medical management, while 22.8% required escalation to endoscopic (11.2%) or surgical (11.6%) intervention. The median time from MU diagnosis to surgical intervention was 12.1 months (IQR 4.9-21.2) after excluding patients who presented with perforation at the time of MU diagnosis. Ulcer perforation occurred in 24 patients and was managed with Graham patch repair or endoscopic techniques. Multivariate analysis showed that female sex (OR 0.31; 95% CI 0.11-0.85; p = 0.035) was associated with a decreased risk of perforation, while smoking resumption at 6 months postoperatively (OR 4.46; 95% CI 1.24-16.08; p 0.025) was associated with an increased risk. Univariate analysis also demonstrated that hand-sewn anastomosis was associated with significantly higher risk of MU perforation compared with linear stapling (OR 4.25, 95% CI 1.70-10.69; p = 0.002).
conclusionAlthough most MUs respond to medical therapy, nearly one-quarter of patients require endoscopic or surgical intervention. Resumption of smoking after surgery and male sex are independently associated with perforation. These findings support early recognition of refractory disease, risk-factor modification, and timely escalation of care.
Indexed as
Identifiers
42133218What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.