ArticleGastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association2026
Adherence to pro-vegetarian dietary patterns and gastric cancer risk: a pooled analysis of the StoP Consortium.
Article in Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundPro-vegetarian (PVG) diets may reduce gastric cancer (GC) risk, but evidence remains limited. We aimed to evaluate the association between three predefined PVG patterns-general (gPVG), healthful (hPVG), and unhealthful (uPVG)-and GC risk stratifying by sex in the context of the Stomach Cancer Pooling (StoP) Project Consortium.
methodsWe analysed data from six case-control studies from the StoP Consortium. The final sample included 1,857 incidents, histologically confirmed GC cases and 5,646 controls. Food intakes were assessed using country-specific food frequency questionnaires, which allowed the estimation of PVG patterns using established scoring methods. Adherence to PVG dietary patterns was classified into quintiles. Logistic mixed models with random intercepts for each study were used to estimate odds ratios (ORs) and 95% confidence intervals (CIs).
resultsCompared to the lowest quintile, the highest quintile of adherence to gPVG was associated with an OR
conclusionsHigher adherence to gPVG and hPVG dietary patterns is associated with lower GC risk, whereas higher adherence to uPVG is associated with increased risk. The inverse association observed for hPVG pattern and the positive association for uPVG were only observed in women. These differential effects of dietary patterns in men and women deserve to be further investigated.
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