ArticleMolecular biology reports2026
Molecular characterization of IMP and NDM resistance genes in carbapenemase-producing Enterobacteriaceae isolates in urine.
Article in Molecular biology reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionExtended-spectrum beta-lactamase and carbapenemase-producing Enterobacteriaceae, implicated in urinary tract infections, represent a major challenge and limit therapeutic options. Our study sought to characterize the genes of resistance to IMP and NDM in urine samples from patients in the city of Ouagadougou by real-time PCR. METHODOLOGY: This cross-sectional study focused on 130 bacterial isolates collected from February to July 2023 at HOSCO and CERBA. The determination of the enterobacterium species was followed by the performance of an antibiogram. Gene detection consisted of the extraction of bacterial DNA and its amplification by real-time PCR.
result60 isolates came from male patients (46.2%) and 70 from female patients (53.8%), for a sex ratio (M/F) of 0.85 and an age between 51 days and 83 years, including 87.7% over 20 years. The most frequent species were respectively Escherichia coli (64.6%), Klebsiella sp. (30.8%), Proteus sp. (3.1%) and Enterobacter cloacae (1.5%). Resistance to imipenem for all Enterobacteriaceae strains was 19.2% and the majority gene was NDM (70%). The IMP gene was rare with only one positive case (0.8%) which was a coexistence of the 2 genes IMP and NDM.
conclusionThe NDM gene could be a cause of resistance to antibiotics, particularly imipenem, and special attention should be paid to Escherichia coli in the fight against the emergence of extended-spectrum β-lactamases. Real-time PCR could serve as a routine analytical technique to facilitate obtaining more reliable results in a short timeframe.
Indexed as
Identifiers
42133148What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.