SynthesisHernia : the journal of hernias and abdominal wall surgery2026
Complications after biosynthetic long-term absorbable mesh implantation for ventral hernia repair in clean and contaminated environments: a systematic review and meta-analysis.
Synthesis in Hernia : the journal of hernias and abdominal wall surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
1 citing paper in PubMed.
- Editorial: Biosynthetic resorbable meshes: a New frontier in abdominal wall hernia repair.Frontiers in surgery · 2026Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundVentral hernia repair (VHR) remains a common yet complex surgical procedure, with substantial recurrence and complication rates. Long-term absorbable biosynthetic meshes have been introduced to provide temporary reinforcement while potentially reducing mesh‑related morbidity.
objectiveThis meta-analysis evaluates the safety and effectiveness of long-term absorbable biosynthetic meshes in VHR by synthesizing both comparative and descriptive studies.
methodsDatabases were searched up to October 2025 for studies on VHR with long-term absorbable biosynthetic mesh. Descriptive studies were pooled using random-effects models to determine event rates. Comparative studies were analyzed using odds-ratios (ORs).
resultsThirty-five descriptive single-arm studies and seventeen comparative studies were included. Descriptive hernia recurrence rate was 11.6% (95%CI 9.3-14.3%), surgical site infection (SSI) 11.8% (95%CI 9.2-15.0%), surgical site occurrence (SSO) 21.9% (95%CI 15.9-29.5%), seroma 9.7% (95%CI 7.2-12.9%), and SSO/SSI requiring surgical-intervention (SSOPI) 9.7% (95%CI 7.6-12.3%). Mesh infection and explantation rates were 0.3% (95%CI 0.0-1.0%) and 0.5% (95%CI 0.0-1.6%) both also in single-arm studies. A significantly lower hazard of recurrence 0.47 (95%CI 0.24-0.93), and a non-significantly lower risk of SSI, SSO, mesh explantation, and SSOPI compared to biologic meshes was found in comparative studies. Absorbable meshes showed a non-significant difference in recurrence rate versus permanent synthetic mesh (OR 0.93, 95%CI 0.57-1.52) but significantly lower odds of mesh explantation (OR 0.46, 95%CI 0.27-0.79).
conclusionsLong-term absorbable biosynthetic meshes show low mesh infection and explantation rates in the available literature. Comparative analyses suggest lower recurrence versus biologic meshes and fewer explantations versus permanent synthetic meshes; however, these findings are based on heterogeneous, predominantly retrospective data with limited follow-up and should not be considered conclusive.
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