ArticleAmerican journal of physiology. Heart and circulatory physiology2026
Heart rate and vascular responses to spontaneous arousals following experimental sleep restriction.
Article in American journal of physiology. Heart and circulatory physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Chronic short sleep duration is associated with cardiovascular disease (CVD) risk, especially in females. The impact of biological sex on hemodynamic reactivity to spontaneous nocturnal arousals following experimental sleep restriction remains largely unknown. We therefore investigated the effect of 9-day 4-h sleep restriction on heart rate (HR) and pulse transit time (PTT) changes following spontaneous arousals in healthy males and females. We hypothesized that HR and PTT reactivity would be augmented following sleep restriction, and these responses would be more robust in females. Nineteen participants (8 females; 23 ± 5 yr) were enrolled into this study, which included two 16-day in-patient studies comprised of sleep restriction (4-h sleep opportunity) and normal sleep (9-h sleep opportunity) study arms. Overnight polysomnography on
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