ArticleJACC. Case reports2026
Physiology-Guided Selective Posteromedial Left Ganglionated Plexus Cardioneuroablation for Functional Paroxysmal Atrioventricular Block.
Article in JACC. Case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Cardioneuroablation for Functional Atrioventricular Block: Let Physiology Lead the Way.JACC. Case reports · 2026Article
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundFunctional atrioventricular (AV) block is a vagally mediated bradyarrhythmia with preserved His-Purkinje conduction. Cardioneuroablation targets parasympathetic inputs as an alternative to pacing. CASE SUMMARY: A 27-year-old woman with recurrent syncope had paroxysmal functional AV block on ambulatory monitoring. Baseline conduction intervals were normal, while programmed atrial stimulation induced supra-Hisian block. Extracardiac vagal stimulation (ECVS) reproducibly triggered high-grade AV block. High-density mapping identified fractionated electrograms at the posteromedial left ganglionated plexus (PMLGP). Selective radiofrequency ablation was performed. After ablation, ECVS no longer induced AV block. The patient remained asymptomatic without recurrence. DISCUSSION: This case demonstrates a physiology-guided cardioneuroablation approach integrating conduction system assessment, ECVS, and fractionation mapping to enable targeted ablation of the PMLGP. TAKE-HOME MESSAGE: Selective PMLGP ablation guided by ECVS and mapping can eliminate functional AV block and avoid permanent pacing.
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