Evidence map›Paper›PMID 42132727›Full record

ArticleJACC. Case reports2026

Acute Changes in Coronary Microvascular Physiology After Supersaturated Oxygen Therapy in Anterior STEMI.

Guillermo J Velazquez Gutierrez, Jhonny I Borrallas Lopez, Jesus G Rodriguez de la Torre, Omar Abdul-Jawad Altisent, Pedro Cepas-Guillem, Eduardo J Flores Umanzor, Xavier Freixa Rofastes, Ander Regueiro, Manel Sabate, Salvatore Brugaletta

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in JACC. Case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Guillermo J Velazquez GutierrezClínic Barcelona, Cardiovascular Clinic Institute, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Barcelona, Spain.
Jhonny I Borrallas LopezClínic Barcelona, Cardiovascular Clinic Institute, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Barcelona, Spain.
Jesus G Rodriguez de la TorreClínic Barcelona, Cardiovascular Clinic Institute, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Barcelona, Spain.
Omar Abdul-Jawad AltisentClínic Barcelona, Cardiovascular Clinic Institute, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Barcelona, Spain; Departament de Medicina i Cièncias Mediques, Universitat de Barcelona, Barcelona, Spain.
Pedro Cepas-GuillemClínic Barcelona, Cardiovascular Clinic Institute, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Barcelona, Spain; Departament de Medicina i Cièncias Mediques, Universitat de Barcelona, Barcelona, Spain.
Eduardo J Flores UmanzorClínic Barcelona, Cardiovascular Clinic Institute, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Barcelona, Spain; Departament de Medicina i Cièncias Mediques, Universitat de Barcelona, Barcelona, Spain.
Xavier Freixa RofastesClínic Barcelona, Cardiovascular Clinic Institute, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Barcelona, Spain; Departament de Medicina i Cièncias Mediques, Universitat de Barcelona, Barcelona, Spain.
Ander RegueiroClínic Barcelona, Cardiovascular Clinic Institute, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Barcelona, Spain; Departament de Medicina i Cièncias Mediques, Universitat de Barcelona, Barcelona, Spain.
Manel SabateClínic Barcelona, Cardiovascular Clinic Institute, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Barcelona, Spain; Departament de Medicina i Cièncias Mediques, Universitat de Barcelona, Barcelona, Spain; CIBER-CV: Biomedical Research Networking Center in Cardiovascular Diseases, Madrid, Spain.
Salvatore BrugalettaClínic Barcelona, Cardiovascular Clinic Institute, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Barcelona, Spain; Departament de Medicina i Cièncias Mediques, Universitat de Barcelona, Barcelona, Spain. Electronic address: sabrugaletta@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMicrovascular dysfunction may persist despite successful primary percutaneous coronary intervention (PCI) in anterior ST-segment elevation myocardial infarction (STEMI). Supersaturated oxygen (SSO CASE SUMMARY: A 74-year-old man presented with anterior STEMI. Primary PCI restored TIMI flow grade 3 after mid-left anterior descending artery occlusion. Post-PCI invasive assessment showed microvascular dysfunction, with hyperemic microvascular resistance of 398 mm Hg/L/min) and index of microcirculatory resistance of 25. After 60 minutes of intracoronary SSO DISCUSSION: Restoration of TIMI flow grade 3 flow does not necessarily reflect effective microvascular reperfusion. In this case, SSO TAKE-HOME MESSAGES: Microvascular dysfunction may persist despite successful PCI in anterior STEMI. Invasive assessment enables real-time evaluation of microvascular function. SSO

Indexed as

acute coronary syndromemyocardial infarctionpercutaneous coronary intervention

Identifiers

PMID42132727
PMCPMC13309699

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.