Article in ACS synthetic biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
9 authors.
Paul M D'AgostinoDepartment of Natural Product Biotechnology, Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Helmholtz Centre for Infection Research (HZI) and Department of Pharmacy at Saarland University, PharmaScienceHub (PSH), Campus E8.1, 66123 Saarbrücken, Germany.ORCID 0000-0002-8323-5416
Roberta R de CastroChair of Technical Biochemistry, Technical University of Dresden, Bergstraße 66, 01069 Dresden, Germany.
Valdet UkaChair of Technical Biochemistry, Technical University of Dresden, Bergstraße 66, 01069 Dresden, Germany.
Kumar SauravLaboratory of Algal Biotechnology, Centre Algatech, Institute of Microbiology of the Czech Academy of Sciences, Novohradská 237, 379 01 Třeboň, Czech Republic.ORCID 0000-0002-7084-4204
Yelyzaveta KriukovaDepartment of Natural Product Biotechnology, Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Helmholtz Centre for Infection Research (HZI) and Department of Pharmacy at Saarland University, PharmaScienceHub (PSH), Campus E8.1, 66123 Saarbrücken, Germany.
Tobias M MilzarekDepartment of Natural Product Biotechnology, Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Helmholtz Centre for Infection Research (HZI) and Department of Pharmacy at Saarland University, PharmaScienceHub (PSH), Campus E8.1, 66123 Saarbrücken, Germany.
Angela SesterDepartment of Natural Product Biotechnology, Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Helmholtz Centre for Infection Research (HZI) and Department of Pharmacy at Saarland University, PharmaScienceHub (PSH), Campus E8.1, 66123 Saarbrücken, Germany.
Maria Paula SchneiderLaboratory of Genomics and Biotechnology, Federal University of Pará, Av. Augusto Correa 1, 66075-110, Belem-PA, Brazil.
Tobias A M GulderDepartment of Natural Product Biotechnology, Helmholtz Institute for Pharmaceutical Research Saarland (HIPS), Helmholtz Centre for Infection Research (HZI) and Department of Pharmacy at Saarland University, PharmaScienceHub (PSH), Campus E8.1, 66123 Saarbrücken, Germany.ORCID 0000-0001-6013-3161
Funding
No grant is acknowledged in the PubMed record.
6 · The paper itself
Abstract
Cyanobacteria have long been recognized as a prolific source of bioactive natural products (NPs). Among these are the furanolides, a structurally diverse class of compounds first discovered in the 1980s. Furanolides are characterized by a γ-butyrolactone core bearing aromatic or aliphatic substituents at the α- and β-positions and an aromatic substituent at the γ-position. Recent advances in understanding the genetic basis of furanolide biosynthesis have enabled genome mining approaches to discover related cryptic furanolide biosynthetic gene clusters (BGCs). In this work, we identified and cloned a cryptic BGC (15.5 kb) from
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
The Maculalactone Biosynthetic Gene Cluster, a Cryptic Furanolide Pathway Revealed in · full record | OpenQuestion