Evidence map›Paper›PMID 42132318›Full record

ArticleJACC. Case reports2026

Intracoronary Electrocardiography During Dobutamine Stress for Functional Assessment of Myocardial Bridging.

Yoshichika Miyazaki, Ami Kimpara, Mitsuhito Soh, Otoya Sekine, Masayuki Aoyama, Nayuka Sumida, Takafumi Nishimura, Kohei Inagawa, Munehisa Sakamoto, Takumi Toya

Abstract readCase Reports
In one paragraph

Article in JACC. Case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yoshichika MiyazakiDepartment of Cardiology, NHO Tokyo Medical Center, Tokyo, Japan.
Ami KimparaDepartment of Cardiology, NHO Tokyo Medical Center, Tokyo, Japan.
Mitsuhito SohDepartment of Cardiology, NHO Tokyo Medical Center, Tokyo, Japan.
Otoya SekineDepartment of Cardiology, NHO Tokyo Medical Center, Tokyo, Japan.
Masayuki AoyamaDepartment of Cardiology, NHO Tokyo Medical Center, Tokyo, Japan.
Nayuka SumidaDepartment of Cardiology, NHO Tokyo Medical Center, Tokyo, Japan.
Takafumi NishimuraDepartment of Cardiology, NHO Tokyo Medical Center, Tokyo, Japan.
Kohei InagawaDepartment of Cardiology, NHO Tokyo Medical Center, Tokyo, Japan.
Munehisa SakamotoDepartment of Cardiology, NHO Tokyo Medical Center, Tokyo, Japan.
Takumi ToyaDepartment of Cardiology, NHO Tokyo Medical Center, Tokyo, Japan; Nishikoyama Toya Medical Clinic-Diabetes and Cardiovascular Care, Tokyo, Japan. Electronic address: tyt0725@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMyocardial bridging (MB) can cause exertional ischemia, but functional assessment is challenging when ischemia is localized and undetected by surface electrocardiography (ECG). CASE SUMMARY: An 83-year-old man with vasospastic angina presented with recurrent exertional chest discomfort. Coronary angiography revealed MB in the mid-left anterior descending artery without significant epicardial stenosis. Intracoronary acetylcholine induced complete occlusion of a diagonal branch with symptom reproduction. Dobutamine stress testing using a pressure-sensor guidewire showed a resting full-cycle ratio ≤0.76 at 20 μg/kg/min, indicating functionally significant ischemia. Surface ECG remained unchanged; however, intracoronary ECG demonstrated marked ST-segment depression distal to the bridged segment, confirming localized ischemia. Switching medical therapy from nifedipine to diltiazem led to symptomatic improvement. TAKE-HOME MESSAGE: Intracoronary ECG performed during dobutamine stress testing may enable direct visualization of localized myocardial ischemia associated with MB, even in the absence of ischemic changes on surface ECG.

Indexed as

intracoronary electrocardiographymyocardial bridgingresting full-cycle ratio

Identifiers

PMID42132318
PMCPMC13184853

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.