Evidence map›Paper›PMID 42132291›Full record

ReviewStatistics in medicine2026

An Overview and Recent Developments in the Analysis of Multistate Processes.

Malka Gorfine, Richard J Cook, Per Kragh Andersen, Terry M Therneau, Pierre Joly, Hein Putter, Maja Pohar Perme, Michal Abrahamowicz, Topic Group 8 “Survival Analysis” of the STRATOS Initiative

Abstract readReview
In one paragraph

Review in Statistics in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Malka GorfineDepartment of Statistics and Operations Research, Tel Aviv University, Tel Aviv, Israel.ORCID https://orcid.org/0000-0002-1577-6624
Richard J CookDepartment of Statistics and Actuarial Science, University of Waterloo, Waterloo, Canada.
Per Kragh AndersenSection of Biostatistics, University of Copenhagen, Copenhagen, Denmark.
Terry M TherneauDivision of Biomedical Statistics and Informatics, Mayo Clinic, Rochester, New York, USA.
Pierre JolyInserm, ISPED, Bordeaux Populations Health Research Center, University of Bordeaux, Bordeaux, France.
Hein PutterDepartment of Biomedical Data Sciences, Leiden University Medical Center, Leiden, the Netherlands.
Maja Pohar PermeDepartment of Biostatistics and Medical Informatics, Medical Faculty, University of Ljubljana, Ljubljana, Slovenia.ORCID https://orcid.org/0000-0002-3412-2642
Michal AbrahamowiczDepartment of Epidemiology, Biostatistics and Occupational Health, McGill University, Montreal, Canada.ORCID https://orcid.org/0000-0002-3172-3952
Topic Group 8 “Survival Analysis” of the STRATOS Initiative

Funding

CIHR FRN 13887Discovery Grant from the Natural Sciences and Engineering Research Council of Canada RGPIN-2017-04207Israel Science Foundation 767/21Slovenian Research and Innovation Agency P3-0154Tel Aviv University Center for AI and Data Science (TAD)
6 · The paper itself

Abstract

Multistate models offer a powerful framework for studying disease processes and can be used to formulate intensity-based and more descriptive marginal regression models. They also represent a natural foundation for the construction of joint models for disease processes and dynamic marker processes, as well as joint models incorporating random censoring and intermittent observation times. This article reviews the ways multistate models can be formed and fitted to life history data. Recent work on pseudo-values and the incorporation of random effects to model dependence on the process history and between-process heterogeneity are also discussed. The software available to facilitate such analyses is listed.

Indexed as

Models, StatisticalHumansRegression AnalysisSoftwarefrailtyprocess historypseudo‐valuesstate occupancy probabilitytime‐dependent covariatestransition intensity

Identifiers

PMID42132291
PMCPMC13174117

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.