ReviewDevelopment (Cambridge, England)2026
The choreography of development: RNA localization across time and space.
Review in Development (Cambridge, England), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
0 citing papers in PubMed.
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Authors and funding
3 authors.
Funding
Abstract
RNA localization is a conserved mechanism essential for development. By linking transport, anchoring and local translation, cells can achieve precise spatial control of gene expression. This coordinated regulation also allows developing, polarized cells to rapidly translate mRNAs in response to local cues. mRNA localization relies on cis-elements within transcripts, trans-acting RNA-binding proteins and active transport by cytoskeletal motors, vesicles and organelles. Across evolution - from Drosophila to mammals - localized transcripts govern embryonic patterning, cell polarity and fate specification. Within the developing nervous system, polarized radial glia, neurons, astrocytes and oligodendrocytes rely on mRNA localization for morphogenesis and circuit formation. Advances in omics and imaging technologies are shedding light on the function of localized transcriptomes in these different models. This Review highlights discoveries across model systems that collectively reveal diverse RNA localization and local translation mechanisms that orchestrate development across time and space.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.