Evidence map›Paper›PMID 42132074›Full record

ArticleTransplant infectious disease : an official journal of the Transplantation Society

Epidemiology and Outcomes of Extrapulmonary Invasive Fungal Infections After Kidney Transplantation in Northern India.

Abdullah, Anupma Kaul, Rungmei Marak, Manas Behera, Narayan Prasad, Manas Patel, Dharmendra Bhaduaria, Ravi Kushwaha, Monika Yachha, Akash Mishra

Abstract read
In one paragraph

Article in Transplant infectious disease : an official journal of the Transplantation Society. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

AbdullahDepartment of Nephrology and Renal Transplantation, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, India.ORCID https://orcid.org/0009-0007-2998-3505
Anupma KaulDepartment of Nephrology and Renal Transplantation, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, India.ORCID https://orcid.org/0000-0002-9994-2326
Rungmei MarakDepartment of Microbiology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, India.ORCID https://orcid.org/0000-0002-8909-4896
Manas BeheraDepartment of Nephrology and Renal Transplantation, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, India.ORCID https://orcid.org/0000-0002-2756-117X
Narayan PrasadDepartment of Nephrology and Renal Transplantation, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, India.ORCID https://orcid.org/0000-0001-9801-0474
Manas PatelDepartment of Nephrology and Renal Transplantation, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, India.
Dharmendra BhaduariaDepartment of Nephrology and Renal Transplantation, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, India.ORCID https://orcid.org/0000-0002-1273-8294
Ravi KushwahaDepartment of Nephrology and Renal Transplantation, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, India.
Monika YachhaDepartment of Nephrology and Renal Transplantation, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, India.
Akash MishraCentre of Biostatistics, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India.ORCID https://orcid.org/0000-0001-8383-8316

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundExtrapulmonary invasive fungal infections (IFIs) in kidney transplant recipients (KTRs) are understudied, particularly in endemic, resource-limited settings. This study evaluated the epidemiology, risk factors, and outcomes of extrapulmonary IFIs in KTRs in northern India.

methodsIn this nested case-control study of 1649 KTRs (2007-2022), microbiologically proven extrapulmonary IFI cases were identified from microbiology and histopathology databases.

resultsExtrapulmonary IFI occurred in 67 KTRs (4.1%). Cryptococcosis (46.3%) and candidiasis (20.9%) were the predominant infections. The central nervous system was the most common site (44.8%), followed by the bloodstream (22.4%). The mean age was 46.78 years, and 85.1% were males. The median time to infection was 55 months posttransplant, and 79.1% of infections occurred beyond 1 year posttransplant. Median estimated glomerular filtration rate (eGFR) was 43 mL/min/1.73 m

conclusionsExtrapulmonary IFIs are late-onset and commonly present as cryptococcal meningitis or candidemia. Diabetes and methylprednisolone pulses increase infection risk, while dissemination and KRT requirement predict mortality.

Indexed as

Invasive Fungal InfectionsKidney TransplantationAdultAntifungal AgentsCase-Control StudiesCryptococcosisFemaleGraft RejectionHumansIndiaMaleMiddle AgedRisk FactorsAntifungal Agentscandidiasiscryptococcosisdisseminated infectionextrapulmonary fungal infectionskidney transplantationsurvival outcomes

Identifiers

PMID42132074
PMCPMC13450239

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.