Evidence map›Paper›PMID 42131892›Full record

Observational studyInfluenza and other respiratory viruses2026

Incidence of Respiratory Syncytial Virus Infection Among Patients Aged Less Than 2 Years: A Retrospective Study From an Italian Southern Region in Years 2018-2023.

Giuseppe Di Martino, Pamela Di Giovanni, Federica Vaccaro, Francesca Romana Cascavilla, Carla Di Marzio, Livia Tognaccini, Edoardo Trebbi, Teresa Aita, Ferdinando Romano, Tommaso Staniscia

Abstract readObservational Study
In one paragraph

Observational study in Influenza and other respiratory viruses, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Giuseppe Di MartinoDepartment of Medicine and Ageing Sciences, "G. d'Annunzio" University of Chieti-Pescara, Chieti, Italy.ORCID https://orcid.org/0000-0001-7047-7611
Pamela Di GiovanniDepartment of Medicine and Ageing Sciences, "G. d'Annunzio" University of Chieti-Pescara, Chieti, Italy.
Federica VaccaroDepartment of Medicine and Ageing Sciences, "G. d'Annunzio" University of Chieti-Pescara, Chieti, Italy.
Francesca Romana CascavillaPost-Graduate School of Hygiene and Preventive Medicine, "G. d'Annunzio" University of Chieti-Pescara, Chieti, Italy.
Carla Di MarzioPost-Graduate School of Hygiene and Preventive Medicine, "G. d'Annunzio" University of Chieti-Pescara, Chieti, Italy.
Livia TognacciniSchool of Public Health, "La Sapienza" University of Rome, Rome, Italy.ORCID https://orcid.org/0009-0001-3110-1336
Edoardo TrebbiSchool of Public Health, "La Sapienza" University of Rome, Rome, Italy.
Teresa AitaLocal Health Authority of L'Aquila, L'Aquila, Italy.
Ferdinando RomanoLocal Health Authority of L'Aquila, L'Aquila, Italy.
Tommaso StanisciaDepartment of Medicine and Ageing Sciences, "G. d'Annunzio" University of Chieti-Pescara, Chieti, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionRespiratory syncytial virus (RSV) is one of the most common viruses infecting nearly all children worldwide within the first 2 years of life, requiring hospitalization for over 80% of cases in infants under the age of 1. The aim of this study was to evaluate the epidemiological impact of RSV infections on hospital admissions among patients aged less than 2 years in the Abruzzo region, Italy. In addition, the analysis on patients aged less than 1 year and the evaluation of direct costs related to RSV admissions were also performed.

methodsA retrospective observational study was performed in Abruzzo, a Southern Italian region. Data related to hospitalizations were extracted from the hospital discharge record (HDRs) of the Abruzzo region, considering all hospitalizations registered from 2018 to 2023. HDRs from patients younger than 2 years of age and diagnosed with RSV were extracted. Hospitalizations were stratified by calendar year and seasonal cycle. In addition, the analysis of costs generated by each admission was performed.

resultsTotally, 1899 hospitalizations for RSV (98.43 admissions/1000 inhabitants aged under 2 years of age) were recorded in the Abruzzo region during the study period. The median length of stay of all the considered hospitalizations was 5 days (IQR 5-5). The year with the highest number of hospitalizations was 2023. The incident rate among patients under 2 years of age rose from 17.42 to 19.39 in 2023 in A2 over 1000 inhabitants. About costs, the total expenditure for hospitalizations strongly increased from €579,047.29 in 2018 to €1,060,018.94 in 2023.

conclusionsThis study highlights the heavy burden of RSV on hospital admissions among patients aged under 2 years in a region of Southern Italy. These results are in line with previously published research, leading to the necessity of the introduction of effective preventive measures.

Indexed as

Respiratory Syncytial Virus InfectionsFemaleHospitalizationHumansIncidenceInfantInfant, NewbornItalyMaleRespiratory Syncytial Virus, HumanRetrospective StudiesSeasonsepidemiologyhospitalizationItalypreventive medicinerespiratory syncytial virus

Identifiers

PMID42131892
PMCPMC13173294

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.