Evidence map›Paper›PMID 42131803›Full record

ArticleFrontiers in pharmacology2026

From medicine cabinets to ecosystems: a Europe-wide assessment of household pharmaceutical waste disposal practices.

Przemyslaw Kardas, Tamas Agh, Disposal Collaborators

Abstract read
In one paragraph

Article in Frontiers in pharmacology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Przemyslaw KardasMedication Adherence Research Center, Department of Family Medicine, Medical University of Lodz, Lodz, Poland.
Tamas AghMedication Adherence Research Group, Center for Health Technology Assessment and Pharmacoeconomic Research, University of Pécs, Pécs, Hungary.
Disposal Collaborators

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Unused and expired household medicines contribute to environmental pollution, avoidable healthcare costs, and public health risks, including antimicrobial resistance. Although regulatory frameworks for pharmaceutical waste disposal exist across Europe, real-world practices remain poorly characterised and unevenly implemented. Comprehensive, contemporary evidence on how household medication disposal systems operate across European countries is lacking. Methods: A Europe-wide, cross-sectional online expert survey was conducted from 17 March to 15 October 2025. Experts in healthcare, pharmacy, regulation, and health policy provided structured information on national legislation, collection systems, disposal practices, public awareness activities, and economic arrangements for unused or expired household medicines. Data were consolidated at the country level and analysed descriptively. Results: Forty valid responses were received from experts across 35 European countries. Dedicated legislation for household pharmaceutical waste was reported in 30 countries, while five lacked specific legal provisions and three reported no formal collection system. Pharmacy-based take-back schemes operated in 31 countries, yet their organisation, funding, and effectiveness varied widely. In eight countries, unused medicines were commonly discarded in household waste. Annual collection rates varied from 12.4 to over 200 g/capita. Extended producer responsibility schemes were reported in six countries and were associated with higher collection volumes and comprehensive national coverage. Public awareness campaigns were reported in 22 countries, but their scope, visibility, and evaluation were inconsistent. Systematic monitoring data were unavailable in most countries, and only seven reported reimbursement mechanisms for pharmacies collecting medicines. Conclusion: Household medication disposal practices across Europe remain highly heterogeneous, reflecting persistent gaps between policy intent and implementation. Inconsistent legislation, limited financing, variable public awareness, and weak monitoring undermine system performance. Coordinated European action is needed to harmonise standards, strengthen financing, and promote environmentally safe disposal of unused and expired household medicines.

Indexed as

environmental impactEuropeextended producer responsibilityhealth policyhousehold pharmaceutical wastemedication optimisationmedicine disposalpharmaceutical pollution

Identifiers

PMID42131803
PMCPMC13161044

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.