Evidence map›Paper›PMID 42131799›Full record

ArticleDepression and anxiety2026

Analysis of Depression and Anxiety in Patients With Tinnitus: A Focus on Specific Age Groups and Sex-Related Differences.

Jing Zhou, Yuehong Liu, Hongbo Xie, Siyi Yang, Yun Jiang, Zhao Han

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Article in Depression and anxiety, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Jing ZhouDepartment of Otorhinolaryngology-Head and Neck Surgery, Huadong Hospital Affiliated Fudan University, Shanghai, 200040, China, fudan.edu.cn.ORCID 0009-0007-4022-5449
Yuehong LiuDepartment of Otorhinolaryngology-Head and Neck Surgery, Huadong Hospital Affiliated Fudan University, Shanghai, 200040, China, fudan.edu.cn.
Hongbo XieDepartment of Otorhinolaryngology-Head and Neck Surgery, Huadong Hospital Affiliated Fudan University, Shanghai, 200040, China, fudan.edu.cn.
Siyi YangDepartment of Otorhinolaryngology-Head and Neck Surgery, Huadong Hospital Affiliated Fudan University, Shanghai, 200040, China, fudan.edu.cn.
Yun JiangDepartment of Otorhinolaryngology-Head and Neck Surgery, Huadong Hospital Affiliated Fudan University, Shanghai, 200040, China, fudan.edu.cn.
Zhao HanDepartment of Otorhinolaryngology-Head and Neck Surgery, Huadong Hospital Affiliated Fudan University, Shanghai, 200040, China, fudan.edu.cn.ORCID 0000-0002-5753-6952

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To investigate the relationships between anxiety, depression, and insomnia and tinnitus severity among high-functioning employed adults, stratified by age and gender, and to describe age- and gender-specific patterns of prevalence and symptom burden in order to support a biopsychosocial framework for understanding tinnitus onset, progression, and clinical management. Methods: An analysis was performed on data from 745 patients with chronic subjective tinnitus, aged 25-60 years, to assess levels of anxiety (HADS-A), depression (HADS-D), insomnia (ISI), and the perceived severity of tinnitus (THI and VAS). Results: The findings showed that anxiety was significantly correlated with the tinnitus Handicap Inventory in younger patients, particularly in men ( Conclusion: The findings indicate that anxiety in younger patients is closely related to tinnitus, whereas depressive symptoms are more prominent among middle-aged and older women. These variations indicate that patients with tinnitus may present different psychological profiles across gender and age groups. Future research may further explore the underlying pathophysiological mechanisms of tinnitus and examine its progression through long-term follow-up to improve understanding of its clinical heterogeneity.

Indexed as

AnxietyAnxiety DisordersDepressionSleep Initiation and Maintenance DisordersTinnitusAdultAge FactorsComorbidityFemaleHumansMaleMiddle AgedPrevalenceSeverity of Illness IndexSex Factorsage-stratified analysisanxietychronic subjective tinnituscomorbiditiesdepressioninsomniaquality of lifesex differences

Identifiers

PMID42131799
PMCPMC13162118

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.