Evidence map›Paper›PMID 42131792›Full record

ReviewNeuro-oncology advances

Cancer-related fatigue among adult patients living with cancer in Ethiopia: A systematic review and meta-analysis.

Yilkal Abebaw Wassie, Berhan Tekeba, Masresha Asmare Techane, Chalachew Adugna Wubneh, Bezawit Dereje Tilahun, Tadele Mesfin Demelash, Fraol Zeleke Desta, Cherugeta Kebede Asfaw, Elsabeth Alemayehu Haile, Simon Zemenfes Hailu and 8 more

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Neuro-oncology advances. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Yilkal Abebaw WassieDepartment of Medical Nursing, School of Nursing, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.ORCID https://orcid.org/0000-0003-4018-1611
Berhan TekebaDepartment of Pediatrics and Child Health Nursing, School of Nursing, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.
Masresha Asmare TechaneDepartment of Pediatrics and Child Health Nursing, School of Nursing, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.
Chalachew Adugna WubnehDepartment of Pediatrics and Child Health Nursing, School of Nursing, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.
Bezawit Dereje TilahunSchool of Medicine, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.
Tadele Mesfin DemelashSchool of Medicine, Asrat Woldeyes Health Science Campus, Debre Berhan University, Debre Berhan, Ethiopia.
Fraol Zeleke DestaSchool of Medicine, College of Medicine and Health Sciences, Salale University, Fitche, Ethiopia.
Cherugeta Kebede AsfawSchool of Medicine, College of Medicine and Health Sciences, Salale University, Fitche, Ethiopia.
Elsabeth Alemayehu HaileSchool of Medicine, College of Medicine and Health Sciences, Mekelle University, Mekelle, Ethiopia.
Simon Zemenfes HailuSchool of Medicine, College of Medicine and Health Sciences, Mekelle University, Mekelle, Ethiopia.
Frehiwot Tekie WoldemichaelSchool of Medicine, College of Medicine and Health Sciences, Mekelle University, Mekelle, Ethiopia.
Yohana Moges MehariSchool of Medicine, College of Medicine and Health Sciences, Mekelle University, Mekelle, Ethiopia.
Henok Dessie WubnehSchool of Medicine, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.
Mulat Alemu BeshadaSchool of Medicine, College of Medicine and Health Sciences, Salale University, Fitche, Ethiopia.
Ermiyas Meskelu AdugnaSchool of Medicine, College of Medicine and Health Sciences, Salale University, Fitche, Ethiopia.
Leul Alemgena YohannesSchool of Medicine, College of Medicine and Health Sciences, Salale University, Fitche, Ethiopia.
Tesfaye Birhanu AbebeSchool of Medicine, College of Medicine and Health Sciences, Salale University, Fitche, Ethiopia.
Tadesse Tarik TamirDepartment of Pediatrics and Child Health Nursing, School of Nursing, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Cancer-related fatigue (CRF) is one of the most common and distressing side effects of cancer and its treatment. Its clinical impact contributes to poorer health outcomes, reduced quality of life, and higher healthcare costs. Although several primary studies have been conducted in Ethiopia, no systematic review has yet synthesized their findings on CRF. Methods: A comprehensive systematic search was conducted across major databases, including HINARI, Science Direct, Embase, Thesis Bank, PubMed/MEDLINE, Google Scholar, and Research Gate. Following a rigorous screening based on predefined inclusion criteria, 7 studies were included. Data extraction and quantitative synthesis were performed using STATA software. Statistical heterogeneity was assessed with Cochran's Results: This systematic review and meta-analysis included 7 studies comprising 2047 participants, with a pooled prevalence of 73.04% (95% CI: 69.00-77.08%). The prevalence was highest in the Hawassa region (77.40%) and among studies conducted before 2020 (73.34%). Cancer-related fatigue was significantly associated with late-stage disease presentation, anemia, depression, and anxiety. Conclusion and Recommendations: Cancer-related fatigue is a significant public health issue in Ethiopia, with a high prevalence, especially in the Hawassa region. Late-stage cancer, anemia, depression, and anxiety were strong predictors of CRF. Routine screening for fatigue and psychological comorbidities should be integrated into oncology care to improve patient outcomes.

Identifiers

PMID42131792
PMCPMC13161574

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.