Evidence map›Paper›PMID 42131616›Full record

ReviewFrontiers in medicine2026

Biomedical optical imaging of acne pathology: from single-modality methods to multimodal integration.

Xing Ren, Jing Yang, Yanan Sun, Qianghua Quan, Peilin Zhang, Yunong Wang, Yi Wang

Abstract readReview
In one paragraph

Review in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Xing Ren *Yunnan Baiyao Group Co., Ltd., Kunming, China.
Jing Yang *Beijing Changping Hospital of Integrated Chinese and Western Medicine, Beijing, China.
Yanan SunExperimental Research Center, China Academy of Chinese Medical Sciences, Beijing, China.
Qianghua QuanYunnan Baiyao Group Co., Ltd., Kunming, China.
Peilin ZhangBeijing Cowisdom Biotechnology Co., Ltd., Beijing, China.
Yunong WangBeijing University of Chinese Medicine Third Affiliated Hospital, Beijing, China.
Yi WangExperimental Research Center, China Academy of Chinese Medical Sciences, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acne vulgaris is a prevalent inflammatory skin disorder, and the objective, timely, and accurate assessment of its severity is critical for guiding standardized treatment. Conventional evaluation methods are often subjective and time-consuming, limiting clinical efficiency. Optical imaging technologies, characterized by non-invasiveness and high resolution, enable the rapid visualization of key pathological features at the microstructural level, including follicular hyperkeratinization, sebaceous hyperactivity, bacterial colonization, and inflammation. Single-modality imaging techniques, such as OCT, RCM, dermoscopy, LSCI, UV fluorescence imaging, and HSI, can delineate various acne-related changes but face limitations in complex clinical settings. In contrast, multimodal imaging integrates complementary techniques to offer a more comprehensive pathological profile, demonstrating significant potential in clinical applications. Future advancements should prioritize enhanced resolution, sensitivity, and integration with artificial intelligence to improve the precision and reliability of acne severity assessment. This review summarizes the photobiological properties of key acne-related biomarkers and their potential to be harnessed through optical imaging for improved diagnosis and management.

Indexed as

acne vulgarisbio-optical signalsmultimodaloptical imagingpathology

Identifiers

PMID42131616
PMCPMC13160823

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.