Evidence map›Paper›PMID 42131609›Full record

ArticleFrontiers in medicine2026

Development and validation of a predictive model for short-term symptom relief after organophosphate poisoning.

Guoliang Huang, Shaobo Zhang, Binbin Wu, Zuxiong Su, Bingwen Li, Po Mao, Shuanghui Hu, Jiangping Li

Abstract read
In one paragraph

Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Guoliang HuangEmergency Center, Anxi County Hospital, Quanzhou, Fujian, China.
Shaobo ZhangEmergency Center, Anxi County Hospital, Quanzhou, Fujian, China.
Binbin WuEmergency Center, Anxi County Hospital, Quanzhou, Fujian, China.
Zuxiong SuEmergency Center, Anxi County Hospital, Quanzhou, Fujian, China.
Bingwen LiEmergency Center, Anxi County Hospital, Quanzhou, Fujian, China.
Po MaoEmergency Center, Anxi County Hospital, Quanzhou, Fujian, China.
Shuanghui HuEmergency Center, Anxi County Hospital, Quanzhou, Fujian, China.
Jiangping LiEmergency Center, Anxi County Hospital, Quanzhou, Fujian, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Acute organophosphate (OP) poisoning outcomes vary significantly despite standard atropine/pralidoxime (PAM) therapy. Early identification of patients likely to improve rapidly could optimize resource allocation and individualized care. Methods: This retrospective study analyzed 138 adult acute OP poisoning cases (2018-2023). Patients were randomly split into training ( Results: Four independent predictors were identified: baseline PSS, admission serum cholinesterase, admission Glasgow Coma Scale (GCS) score, and major comorbidities. The nomogram showed strong discrimination (optimism-corrected AUC 0.930 in the training cohort; AUC 0.905 in the validation cohort) and good calibration (MAE 0.034 and 0.066). Decision-curve analysis showed positive net benefit over treat-all and treat-none across clinically relevant thresholds. Conclusion: We developed and validated a practical nomogram predicting 48-h symptom relief in acute OP poisoning. This tool can enhance early risk stratification, guide clinical decisions, and support efficient ICU resource utilization.

Indexed as

cholinesterase activityGlasgow Coma ScaleLASSO regressionnomogramorganophosphate poisoningoutcomessymptom resolution

Identifiers

PMID42131609
PMCPMC13160850

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.