Evidence map›Paper›PMID 42131569›Full record

ArticleFrontiers in human neuroscience2026

Relating brain function to cognitive-visuomotor integration performance in working-aged adults with persisting concussion symptoms.

Miracle E Ozzoude, Diana J Gorbet, Alison K Macpherson, Lauren E Sergio

Abstract read
In one paragraph

Article in Frontiers in human neuroscience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Miracle E OzzoudeInstitute for Neuroscience and Cardiovascular Research, University of Edinburgh, Edinburgh, United Kingdom.
Diana J GorbetSchool of Kinesiology and Health Science, Faculty of Health, York University, Toronto, ON, Canada.
Alison K MacphersonSchool of Kinesiology and Health Science, Faculty of Health, York University, Toronto, ON, Canada.
Lauren E SergioSchool of Kinesiology and Health Science, Faculty of Health, York University, Toronto, ON, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: In everyday life we interact with our environment in an indirect way, where there is a mapping between the viewed goal of our action and the required movement (e.g., using a computer mouse). Such tasks require cognitive- motor integration (CMI), where rules dictate the relationship between perception and action. Previous research with primarily young adult male athletes has demonstrated that the underlying movement and cognitive control networks that rely on intact frontal, parietal, and subcortical brain region connectivity may be compromised following concussion, resulting in an impaired ability to engage in complex movements. Here we investigate whether such relationships also exist in working-aged adults with persistent post-concussion symptoms (PPCS). Methods: Twenty-two individuals (17 females) performed two visuomotor tasks: one requiring direct (standard) interaction with visual targets, and one comprising a plane-change and feedback reversal (non-standard interaction) between viewed target and required hand motion (CMI). PPCS and dizziness were related to brain network function via resting state functional connectivity (RSFC) in six networks, structural integrity via cortical thickness in CMI-related brain regions, and white matter tract integrity via diffusion tensor imaging. Results: We observed that lower cortical thickness in the inferior and superior parietal cortices were associated with dizziness and impaired non-standard visuomotor performance, respectively. Furthermore, increased PPCS severity was associated with hyperconnectivity within the visual, sensorimotor control, frontoparietal control, and dorsal attention networks, while hyperconnectivity within the salience ventral attention network was associated with better non-standard visuomotor performance. Lastly, we found that lower white matter tract integrity in several long associative, projection, and commissural tracts were associated with poor cognitive-motor integration performance, PPCS severity, and dizziness. Discussion: These preliminary findings characterize the impact of PPCS on structure and function underlying impaired visuomotor performance.

Indexed as

brain networkscognitive-motor integrationconcussioncortexeye-hand coordination

Identifiers

PMID42131569
PMCPMC13161089

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.