Evidence map›Paper›PMID 42131498›Full record

ArticlePRX life2026

Cell rearrangement progression along the apical-basal axis is linked with 3D epithelial tissue structure.

Erika M Kusaka, Sassan Ostvar, Xiaoyun Liu, Xun Wang, Tianyi Liu, Karen E Kasza

Abstract read
In one paragraph

Article in PRX life, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Apico-basal intercalations enable the integrity of curved epithelia.Computational and structural biotechnology journal · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Erika M KusakaDepartment of Mechanical Engineering, Columbia University, New York, NY.
Sassan OstvarDepartment of Mechanical Engineering, Columbia University, New York, NY.
Xiaoyun LiuDepartment of Mechanical Engineering, Columbia University, New York, NY.
Xun WangDepartment of Mechanical Engineering, Columbia University, New York, NY.
Tianyi LiuDepartment of Mechanical Engineering, Columbia University, New York, NY.
Karen E KaszaDepartment of Mechanical Engineering, Columbia University, New York, NY.

Funding

Mechanisms coordinating cell behaviors within tissues during developmentR35GM138380 · NIGMS · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI Karen Kasza · 2020 to 2026
$2.8M
NIGMS NIH HHS R35 GM138380
6 · The paper itself

Abstract

Epithelial tissues undergo extensive structural remodeling during embryonic development. Tissue remodeling is often enabled by oriented cell rearrangements that are linked with patterns of mechanical stresses in the tissue and with tissue mechanical properties. Cell rearrangements and their links to tissue structure have largely been studied at the apical side of tissues at the level of adherens junctions. Less is known about the involvement of basolateral domains in cell rearrangements. Here we use live confocal imaging to quantify cell rearrangements, cell packing structure, and cell morphology in 3D in the converging and extending

Indexed as

apical-basal polarityconvergent extensionDrosophilaepithelial morphogenesisgermband extensiontissue remodeling

Identifiers

PMID42131498
PMCPMC13166131

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.