ArticleReports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology2026
Radiation-induced malignancies from simultaneous integrated boost-VMAT for oropharyngeal cancer delivered with four different fractionation schemes.
Article in Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Late side-effects including carcinogenesis may appear following head-and-neck tumor irradiation. This study estimated the risk for developing second malignancies in heavily exposed tissues from simultaneous integrated boost (SIB) volumetric modulated arc therapy (VMAT) for oropharyngeal carcinoma. Materials and methods: Sixteen oropharyngeal carcinoma patients needing bilateral neck irradiation were included. A three-level SIB-VMAT technique with 6-MV photons was applied. Four different treatment plans were created per patient. The first plan (VMAT Results: For 50-year-old males and females undergoing VMAT Conclusions: The risks for radiation-induced malignancies following SIB-VMAT for oropharyngeal cancer were found to be comparable with the baseline risks for general population. Hypofractionated treatment restricted the probability for carcinogenesis.
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