ArticleReports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology2026
Impact of diabetes mellitus in patients undergoing radiation therapy for head and neck cancer.
Article in Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: The study aims to find the impact of diabetes mellitus (DM) in patients undergoing radiation therapy (RT) for head and neck cancer (HNC). Materials and methods: The retrospective cohort study analysed 346 HNC patients who received definitive or adjuvant RT with or without chemotherapy from January 2013 to December 2023. The patients were categorized into DM (n = 84) and non-DM (n = 262) group. This study analysed baseline characteristics, compliance, toxicities, and overall survival (OS). Results: A total of 12 (14.3%) patients in the DM arm and 24 (9.2%) in the non-DM arm did not complete the scheduled RT. Treatment breaks (> 2 days) occurred in 49 patients (58.3%) in the DM arm Conclusions: This study showed that HNC patients with DM undergoing RT are more susceptible to acute and late toxicities, poor compliance to treatment and significantly poor OS compared to non-DM group.
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