Evidence map›Paper›PMID 42131378›Full record

ArticleJournal of the Association of Medical Microbiology and Infectious Disease Canada = Journal officiel de l'Association pour la microbiologie medicale et l'infectiologie Canada2026

Antibiotic prescribing for aspiration pneumonia in the intensive care unit.

Elaf Alzarnougi, Mansor Binhashr, Rasha Alshawaf, Si Yuan Pan, Pardeep Singh, Amy Bartholomew, Dominik Mertz, Mark Loeb

Abstract read
In one paragraph

Article in Journal of the Association of Medical Microbiology and Infectious Disease Canada = Journal officiel de l'Association pour la microbiologie medicale et l'infectiologie Canada, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Elaf AlzarnougiDepartment of Medicine, McMaster University, Hamilton, Ontario, Canada.
Mansor BinhashrDepartment of Medicine, McMaster University, Hamilton, Ontario, Canada.
Rasha AlshawafDepartment of Medicine, McMaster University, Hamilton, Ontario, Canada.
Si Yuan PanDepartment of Medicine, McMaster University, Hamilton, Ontario, Canada.
Pardeep SinghDepartment of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada.
Amy BartholomewDepartment of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada.
Dominik MertzDepartment of Medicine, McMaster University, Hamilton, Ontario, Canada.
Mark LoebDepartment of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Antibiotics are frequently prescribed for aspiration pneumonia in ICU patients. We sought to determine the proportion of ICU patients treated for aspiration pneumonia who meet the diagnostic criteria. Methods: A retrospective review of electronic medical records was conducted in adult patients who were admitted to one of two intensive care units at an Ontario tertiary care hospital between June 1, 2022, and October 1, 2023. Patients who were exposed to antibiotics were first identified and then systematically assessed using electronic medical records to identify occurrences in which aspiration was suspected and antibiotics were potentially used to treat aspiration pneumonia within 14 days of the aspiration event. For each episode, we assessed whether patients met the criteria for either confirmed or suspected aspiration pneumonia. Factors associated with inappropriate prescribing were determined. Results: Of 497 patients treated with antibiotics, 104 (22.0%) were treated for aspiration pneumonia. More than one-half (67 patients, 64.4%) were categorized as either confirmed or suspected aspiration pneumonia. There were 35.6% cases (37 of 104) in which antibiotic courses were prescribed for aspiration pneumonia without meeting the criteria for confirmed or suspected cases. Factors associated with not meeting criteria included prescribing by attending physicians compared with residents or fellows (OR 1.53 [95% CI 0.63 to 3.67], Conclusions: Inappropriate antibiotic prescribing for aspiration pneumonia remains common in the ICU.

Indexed as

antibiotic stewardshipaspiration pneumoniaICUpneumonia

Identifiers

PMID42131378
PMCPMC13167169

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.