ArticlePsychology of sexual orientation and gender diversity2026
Health Disparities Between Stress-Related Mental Health Conditions and Chronic Physical Health Conditions Among Hispanic and Latinx Sexual and Gender Minority Individuals: Findings from the All of Us Research Program.
Article in Psychology of sexual orientation and gender diversity, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Sexual and gender minority individuals experience significant health disparities, including elevated rates of stress-related mental health conditions and chronic physical health conditions. Among Hispanic and Latinx populations, these disparities are particularly pronounced. They face intersecting minority stressors related to ethnicity, sexual orientation, and gender identity. This study examined the prevalence and association between stress-related mental health conditions and chronic physical health conditions among sexual and gender minorities in both a full sample and a Hispanic/Latinx subsample. Using data from 413,360 participants in the All of Us Research Program, we assessed the likelihood of reporting chronic physical health conditions among sexual and gender minorities with stress-related mental health conditions. Logistic regression analyses were performed, adjusting for age and body mass index, as these are known covariates. Findings indicate that, in the full sample, sexual and gender minorities were more likely to report chronic physical health conditions compared to their cisgender and heterosexual counterparts. Within the Hispanic/Latinx population, sexual minorities groups with stress-related mental health conditions were over twice as likely to report chronic physical health conditions compared to those without such conditions. The association between gender minority status and chronic physical health conditions was stronger than that observed for sexual minority status, underscoring the compounded health risks faced by gender minority individuals. These findings point the urgent need for targeted healthcare interventions. They also highlight important implications for public health policy and clinical practice, particularly the development of culturally responsive strategies to reduce health disparities among sexual and gender minority individuals.
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