Evidence map›Paper›PMID 42131297›Full record

ArticleThe Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale2026

Exploring the Relationship Between Comorbidities and Prolonged Viral Shedding in COVID-19: A Cycle Threshold Value-Based Investigation.

Rudi Wisaksana, Patrick Philo, Floriyani Indra Putri, Chrisan Bimo Prayuda, Evan Susandi, Leonardus Widyatmoko, Bachti Alisjahbana, Iceu Dimas Kulsum, Yovita Hartantri

Abstract read
In one paragraph

Article in The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Exploring the Relationship Between Comorbidities and Prolonged Viral Shedding in COVID-19: A Cycle Threshold Value-Based Investigation.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Rudi WisaksanaDivision of Tropical and Infectious Disease, Department of Internal Medicine, Faculty of Medicine Universitas Padjadjaran, Hasan Sadikin General Hospital, Bandung, Indonesia.ORCID https://orcid.org/0009-0007-4520-9093
Patrick PhiloDepartment of Internal Medicine, Faculty of Medicine Universitas Padjadjaran, Hasan Sadikin General Hospital, Bandung, Indonesia.
Floriyani Indra PutriDepartment of Internal Medicine, Faculty of Medicine Universitas Padjadjaran, Hasan Sadikin General Hospital, Bandung, Indonesia.
Chrisan Bimo PrayudaDepartment of Internal Medicine, Faculty of Medicine Universitas Padjadjaran, Hasan Sadikin General Hospital, Bandung, Indonesia.ORCID https://orcid.org/0009-0009-4736-901X
Evan SusandiDepartment of Internal Medicine, Faculty of Medicine Universitas Padjadjaran, Hasan Sadikin General Hospital, Bandung, Indonesia.ORCID https://orcid.org/0000-0002-0178-7138
Leonardus WidyatmokoDepartment of Clinical Pathology, Faculty of Medicine Universitas Padjadjaran, Hasan Sadikin General Hospital, Bandung, Indonesia.
Bachti AlisjahbanaDivision of Tropical and Infectious Disease, Department of Internal Medicine, Faculty of Medicine Universitas Padjadjaran, Hasan Sadikin General Hospital, Bandung, Indonesia.
Iceu Dimas KulsumDivision of Pulmonology and Critical Illness, Department of Internal Medicine, Faculty of Medicine Universitas Padjadjaran, Hasan Sadikin General Hospital, Bandung, Indonesia.
Yovita HartantriDivision of Tropical and Infectious Disease, Department of Internal Medicine, Faculty of Medicine Universitas Padjadjaran, Hasan Sadikin General Hospital, Bandung, Indonesia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: We aim to investigate which of the comorbidities is associated with prolonged viral RNA shedding among hospitalized patients with COVID-19 illness. Patients and Methods: We conducted a retrospective cohort study of COVID-19 patients in Hasan Sadikin General Hospital, Bandung, from March 2020 to April 2022. Data of ORF1b Ct value measurements were collected from the 1 Results: We included a total of 279 patients with a median age of 55-year-old, and male patients were the majority included. However, 68% of the original cohort was excluded due to having only a single Ct result. Based on the ORF1b Ct value data, most patients within each comorbidity group demonstrated increasing Ct values from Week 1 ( Conclusion: This study shows that COVID-19 patients with HIV-AIDS have prolonged viral shedding compared to patients with other comorbidities.

Indexed as

autoimmuneCOVID-19 infectionCt valueHIV–AIDSprolonged viral shedding

Identifiers

PMID42131297
PMCPMC13161999

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.