ArticleFrontiers in microbiology2026
Differential antimicrobial activity of two LL37 derivatives against periodontal bacteria, including enhanced efficacy against
Article in Frontiers in microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- LL-37-based oral antimicrobial therapeutics: translational challenges and future directions-a narrative review.Odontology · 2026Review
- Targeting Bacterial Infections in Periodontal Disease: From Conventional Antibiotics to Next-Generation Therapeutics.Antibiotics (Basel, Switzerland) · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Periodontitis is a plaque-induced condition that causes irreparable damage to the supporting tissues of the teeth, and tobacco smoking is a recognized exacerbating and risk factor. Antibiotic-resistant bacteria are a consequence of antibiotic overuse. Antimicrobial peptides (AMPs) are innate immune system molecules that show promise in combating antibiotic resistance. Methods: The current work investigated the efficiency of two synthetic derivatives of AMP human cathelicidin LL37, FK13a1-NH2 and KR12-NH2, in inhibiting target periodontal bacteria such as Results: The results of the investigation showed that the two synthesized AMPs effectively inhibited the growth of Conclusion: Peptides applied in the presence of CSE were effective against
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.