Evidence map›Paper›PMID 42130854›Full record

ArticleRSC advances2026

Hyaluronic acid-modified Fe-based metal-organic framework loaded with cisplatin for targeted lung cancer therapy.

Ammar Saleem, Komal Zaman Khan, Eman Fayad, Aurang Zaib, Ghazanfar Abbas, Dalal Nasser Binjawhar, Ali Junaid, Muhammad Naeem Ashiq, Zahid Shafiq, Hua Li Qin

Abstract read
In one paragraph

Article in RSC advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ammar SaleemSchool of Chemistry, Chemical Engineering and Life Sciences, Wuhan University of Technology Wuhan 430070 China qinhuali@whut.edu.cn.ORCID https://orcid.org/0000-0003-0083-2432
Komal Zaman KhanSchool of Chemistry, Chemical Engineering and Life Sciences, Wuhan University of Technology Wuhan 430070 China qinhuali@whut.edu.cn.
Eman FayadDepartment of Biotechnology, College of Science, Taif University P.O. Box 11099 Taif 21944 Saudi Arabia.
Aurang ZaibSchool of Chemistry, Chemical Engineering and Life Sciences, Wuhan University of Technology Wuhan 430070 China qinhuali@whut.edu.cn.
Ghazanfar AbbasSchool of Chemistry, Chemical Engineering and Life Sciences, Wuhan University of Technology Wuhan 430070 China qinhuali@whut.edu.cn.
Dalal Nasser BinjawharDepartment of Chemistry, College of Science, Princess Nourah Bint Abdulrahman University P.O. Box 84428 Riyadh 11671 Saudi Arabia.
Ali JunaidInstitute of Chemical Sciences, Bahauddin Zakariya University Multan 60800 Pakistan zahidshafiq@bzu.edu.pk.
Muhammad Naeem AshiqInstitute of Chemical Sciences, Bahauddin Zakariya University Multan 60800 Pakistan zahidshafiq@bzu.edu.pk.ORCID https://orcid.org/0000-0001-8561-3065
Zahid ShafiqInstitute of Chemical Sciences, Bahauddin Zakariya University Multan 60800 Pakistan zahidshafiq@bzu.edu.pk.ORCID https://orcid.org/0000-0003-4088-8297
Hua Li QinSchool of Chemistry, Chemical Engineering and Life Sciences, Wuhan University of Technology Wuhan 430070 China qinhuali@whut.edu.cn.ORCID https://orcid.org/0000-0002-6609-0083

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lung cancer is still the most common cause of cancer fatalities around the world. To address these issues, we fabricated a cisplatin-containing hyaluronic acid-modified Fe-MOF that was designed to release drugs in response to changes in pH and actively target lung cancer cells. The incorporation of HA, which specifically binds to CD44 receptors that are overexpressed on the surface of lung cancer cells, improves cellular uptake and therapeutic effectiveness. The pH-dependent behavior is confirmed by

Identifiers

PMID42130854
PMCPMC13162095

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.