ArticleInternational journal of breast cancer2026
Implementation of a Multidisciplinary Protocol for the Safe Handling of Iodine-125 Radioactive Seeds in the Pathology Laboratory.
Article in International journal of breast cancer, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
1 citing paper in PubMed.
- Implementation of a Multidisciplinary Protocol for the Safe Handling of Iodine-125 Radioactive Seeds in the Pathology Laboratory.International journal of breast cancer · 2026Article
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Iodine-125 radioactive seeds (I Methods: A protocol involving Radiology, Surgery, Nuclear Medicine, and Pathology was established to ensure proper documentation, transport, radiographic confirmation, seed retrieval, and incident reporting. All I Results: A total of 146 seeds were retrieved from 130 specimens from 123 patients. Most samples were lumpectomies (89.2%); 24.4% of patients received neoadjuvant therapy. Invasive carcinoma accounted for 82.3% of diagnoses. Double-seed placement was used in 16 cases. Positive margins occurred in 9.1%, and 7.2% required reoperation. There were 18 incidents (14.6%): Category I, 10 (55.6%), mainly documentation errors or seed displacement within containers; and Category II, 8 (44.4%), mostly seeds hidden within tissue slices. Nuclear Medicine was consulted in 11 cases. Importantly, no seeds were lost. No significant associations were found between incidents and clinicopathological variables. Conclusions: The multidisciplinary protocol ensured safe and efficient handling of I
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