ArticleClinical case reports2026
Pulmonary Aspergillosis Treated With Oral Amphotericin B (MAT2203) in a Patient With HIV-Related Cryptococcal Meningitis.
Enock Kagimu, Elizabeth Senkoro, Jane Gakuru, Morris K Rutakingirwa, David R Boulware, David B Meya, Richard Kwizera
Abstract read
In one paragraphArticle in Clinical case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
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3 · Its place in the literatureWho cites it
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4 · The recordCorrections and comments
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5 · Who and what moneyAuthors and funding
7 authors.
Elizabeth SenkoroChronic Diseases Clinic of Ifakara Ifakara Health Institute Ifakara town Tanzania.
Jane GakuruInfectious Diseases Institute, College of Health Sciences Makerere University Kampala Uganda.
David R BoulwareDivision of Infectious Diseases and International Medicine, Department of Medicine University of Minnesota Minneapolis Minnesota USA.
David B MeyaInfectious Diseases Institute, College of Health Sciences Makerere University Kampala Uganda.
Funding
NPGH LEADERs YR12: OBSSR (Greenberg, Ngwafong Mukere) & NIBIB (Lee)D43TW009345 · FIC · UNIVERSITY OF WASHINGTON · PI Dibyadyuti Datta, Chandy C. John · 2017 to 2026
$15.2MImproving Diagnostics and Neurocognitive Outcomes in HIV/AIDS-related MeningitisR01NS086312 · NINDS · UNIVERSITY OF MINNESOTA · PI David R Boulware, David Bisagaya Meya · 2013 to 2026
$8.3MDetermining the performance and accuracy of SILVAMP TB LAM and cost-effectiveness of diagnostic testing for TB meningitis.R01AI170158 · NIAID · UNIVERSITY OF MINNESOTA · PI Nathan Bahr · 2022 to 2026
$3.5MTB Meningitis: Evaluating CSF Immunology to Discover Hidden Disease and Potential Immunomodulatory TherapiesR01AI162786 · NIAID · UNIVERSITY OF MINNESOTA · PI BOULWARE, DAVID R, MEYA, DAVID BISAGAYA · 2021 to 2025
$3.3MEncochleated Oral Amphotericin for Cryptococcal Meningitis TrialR01NS110519 · NINDS · UNIVERSITY OF MINNESOTA · PI BOULWARE, DAVID R, MEYA, DAVID BISAGAYA · 2019 to 2022
$2.6MMinnesota-Makerere-Mbarara Neuro-Infectious Disease Research Training ConsortiumD43TW012266 · FIC · UNIVERSITY OF MINNESOTA · PI David R Boulware, David Bisagaya Meya · 2024 to 2026
$747kMidcareer Mentoring for Clinical Research in HIV/AIDS-related cryptococcal and TB meningitisK24AI184270 · NIAID · UNIVERSITY OF MINNESOTA · PI David R Boulware · 2024 to 2026
$648kFIC NIH HHS D43 TW009345FIC NIH HHS D43 TW012266NIAID NIH HHS K24 AI184270NIAID NIH HHS R01 AI162786NIAID NIH HHS R01 AI170158NINDS NIH HHS R01 NS086312NINDS NIH HHS R01 NS110519
6 · The paper itselfAbstract
The case highlights the need to consider aspergillosis in patients with cryptococcal infections and unexplained respiratory symptoms, as well as in smear-negative pulmonary tuberculosis. When standard triazoles are unavailable, novel oral amphotericin B (MAT2203) successfully treated both invasive pulmonary aspergillosis and cryptococcosis in this case of coinfection, warranting further evaluation.
Indexed as
amphotericin Bchronic pulmonary aspergillosiscryptococcal meningitisfungal infectionsHIVinvasive pulmonary aspergillosis
Identifiers
PMID42130792
PMCPMC13161983
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