Evidence map›Paper›PMID 42130747›Full record

ArticleNational science review2026

DISC1 mutant macaques capture behavioral and neural hallmarks of psychiatric disease.

Wenjia Zhou, Jiayu Sun, Guo-Long Zuo, Yijun Cai, Yang Li, Puzhe Li, Xinyue Tan, Chengfeng Wu, Runze Zhang, Ling Zhuang and 13 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in National science review, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors.

Wenjia ZhouSchool of Life Science and Technology, ShanghaiTech University, Shanghai 201210, China.
Jiayu SunInstitute of Neuroscience, Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences, Shanghai 200031, China.
Guo-Long ZuoSchool of Life Science and Technology, ShanghaiTech University, Shanghai 201210, China.ORCID https://orcid.org/0000-0003-1214-8849
Yijun CaiInstitute of Neuroscience, Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences, Shanghai 200031, China.
Yang LiSchool of Life Science and Technology, ShanghaiTech University, Shanghai 201210, China.
Puzhe LiSchool of Life Science and Technology, ShanghaiTech University, Shanghai 201210, China.
Xinyue TanSchool of Life Science and Technology, ShanghaiTech University, Shanghai 201210, China.
Chengfeng WuInstitute of Neuroscience, Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences, Shanghai 200031, China.
Runze ZhangInstitute of Neuroscience, Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences, Shanghai 200031, China.
Ling ZhuangInstitute of Neuroscience, Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences, Shanghai 200031, China.
Xiaochun WangInstitute of Neuroscience, Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences, Shanghai 200031, China.
Yanhong NieInstitute of Neuroscience, Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences, Shanghai 200031, China.
Yan WangInstitute of Neuroscience, Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences, Shanghai 200031, China.
Wen FangInstitute of Neuroscience, Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences, Shanghai 200031, China.
Chengyu LiLingang Laboratory, Shanghai 201103, China.
Zheng WangSchool of Psychological and Cognitive Sciences, Beijing Key Laboratory of Behavior and Mental Health, State Key Laboratory of General Artificial Intelligence, IDG/McGovern Institute for Brain Research, Peking-Tsinghua Center for Life Sciences, Peking University, Beijing 100871, China.
Ji HuSchool of Life Science and Technology, ShanghaiTech University, Shanghai 201210, China.
Hung-Chun ChangLingang Laboratory, Shanghai 201103, China.
Zhiqi XiongSchool of Life Science and Technology, ShanghaiTech University, Shanghai 201210, China.
Ian Max AndolinaInstitute of Neuroscience, Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences, Shanghai 200031, China.
Liping WangInstitute of Neuroscience, Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences, Shanghai 200031, China.
Qiang SunInstitute of Neuroscience, Center for Excellence in Brain Science and Intelligence Technology, Chinese Academy of Sciences, Shanghai 200031, China.ORCID https://orcid.org/0000-0002-3359-9465
Zhen-Ge LuoSchool of Life Science and Technology, ShanghaiTech University, Shanghai 201210, China.ORCID https://orcid.org/0000-0001-5037-0542

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Schizophrenia is a devastating and complex neurological disorder with poorly understood neurodevelopmental origins. Current rodent models often fail to fully capture human symptomology, hindering therapeutic development. We generated a germline-transmissible

Indexed as

comorbidityDISC1fluoxetineneurological disordersnon-human primatesynaptic dysfunction

Identifiers

PMID42130747
PMCPMC13166873

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.