Evidence map›Paper›PMID 42130746›Full record

ArticleNational science review2026

Cross-domain transfer of trehalose biosynthesis genes contributes to adaptation in high-altitude environments.

Yaohai Wang, Jiahao Ni, Jiao Pan, Ruobing Feng, Weiyi Li, Xuetao Zhang, Chao Gao, Lijian Liao, Zhirong Zhang, Hongwei Yue and 25 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in National science review, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

35 authors.

Yaohai WangKey Laboratory of Evolution and Marine Biodiversity (Ministry of Education), Institute of Evolution and Marine Biodiversity, Ocean University of China, Qingdao 266003, China.
Jiahao NiKey Laboratory of Evolution and Marine Biodiversity (Ministry of Education), Institute of Evolution and Marine Biodiversity, Ocean University of China, Qingdao 266003, China.
Jiao PanKey Laboratory of Evolution and Marine Biodiversity (Ministry of Education), Institute of Evolution and Marine Biodiversity, Ocean University of China, Qingdao 266003, China.
Ruobing FengKey Laboratory of Evolution and Marine Biodiversity (Ministry of Education), Institute of Evolution and Marine Biodiversity, Ocean University of China, Qingdao 266003, China.
Weiyi LiDepartment of Genetics, Stanford University School of Medicine, Stanford, CA 94305, USA.ORCID https://orcid.org/0000-0002-1168-7093
Xuetao ZhangKey Laboratory of Marine Drugs, the Ministry of Education of China, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, China.
Chao GaoKey Laboratory of Evolution and Marine Biodiversity (Ministry of Education), Institute of Evolution and Marine Biodiversity, Ocean University of China, Qingdao 266003, China.
Lijian LiaoKey Laboratory of Evolution and Marine Biodiversity (Ministry of Education), Institute of Evolution and Marine Biodiversity, Ocean University of China, Qingdao 266003, China.
Zhirong ZhangKey Laboratory of Evolution and Marine Biodiversity (Ministry of Education), Institute of Evolution and Marine Biodiversity, Ocean University of China, Qingdao 266003, China.
Hongwei YueKey Laboratory of Evolution and Marine Biodiversity (Ministry of Education), Institute of Evolution and Marine Biodiversity, Ocean University of China, Qingdao 266003, China.
Kexin ZhangKey Laboratory of Evolution and Marine Biodiversity (Ministry of Education), Institute of Evolution and Marine Biodiversity, Ocean University of China, Qingdao 266003, China.
Lin ZhangKey Laboratory of Evolution and Marine Biodiversity (Ministry of Education), Institute of Evolution and Marine Biodiversity, Ocean University of China, Qingdao 266003, China.
Chunhui FengKey Laboratory of Evolution and Marine Biodiversity (Ministry of Education), Institute of Evolution and Marine Biodiversity, Ocean University of China, Qingdao 266003, China.
Dongji YaoKey Laboratory of Evolution and Marine Biodiversity (Ministry of Education), Institute of Evolution and Marine Biodiversity, Ocean University of China, Qingdao 266003, China.
Yumin HanKey Laboratory of Evolution and Marine Biodiversity (Ministry of Education), Institute of Evolution and Marine Biodiversity, Ocean University of China, Qingdao 266003, China.
Xunrong LiQingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, Qingdao 266101, China.
Xuan ZhouQingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, Qingdao 266101, China.
Ziguang DengKey Laboratory of Evolution and Marine Biodiversity (Ministry of Education), Institute of Evolution and Marine Biodiversity, Ocean University of China, Qingdao 266003, China.
Jia ZhangQingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, Qingdao 266101, China.
Pin ZhouQingdao Single-Cell Biotech. Co., Ltd., Qingdao 266100, China.
Gongchao JingQingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, Qingdao 266101, China.
Yu ZhangKey Laboratory of Evolution and Marine Biodiversity (Ministry of Education), Institute of Evolution and Marine Biodiversity, Ocean University of China, Qingdao 266003, China.ORCID https://orcid.org/0000-0001-9179-0922
Lingyun ChenCollege of Life Science, Northwest Normal University, Lanzhou 730070, China.
Xuming PanLaboratory of Protozoology, Harbin Normal University, Harbin 150025, China.
Xiangrui ChenSchool of Marine Science, Ningbo University, Ningbo 315211, China.
Yang BaiMinistry of Education Key Laboratory of Ecology and Resource Use of the Mongolia Plateau, Inner Mongolia University, Hohhot 010021, China.
Ying YanKey Laboratory of Evolution and Marine Biodiversity (Ministry of Education), Institute of Evolution and Marine Biodiversity, Ocean University of China, Qingdao 266003, China.
Jie HuangState Key Laboratory of Lake and Watershed Science for Water Security, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan 430072, China.
Zhiqiang YeSchool of Life Sciences, Central China Normal University, Wuhan 430079, China.
Xiaopeng ShenCollege of Life Sciences, Anhui Normal University, Wuhu 241000, China.ORCID https://orcid.org/0000-0002-6116-635X
Miao TianKey Laboratory of Evolution and Marine Biodiversity (Ministry of Education), Institute of Evolution and Marine Biodiversity, Ocean University of China, Qingdao 266003, China.ORCID https://orcid.org/0000-0001-9086-1872
Rebecca A ZufallDepartment of Biology and Biochemistry, University of Houston, Houston TX 77204, USA.
Pingyuan WangKey Laboratory of Evolution and Marine Biodiversity (Ministry of Education), Institute of Evolution and Marine Biodiversity, Ocean University of China, Qingdao 266003, China.
Michael LynchBiodesign Center for Mechanisms of Evolution, Arizona State University, Tempe AZ 85287, USA.
Hongan LongKey Laboratory of Evolution and Marine Biodiversity (Ministry of Education), Institute of Evolution and Marine Biodiversity, Ocean University of China, Qingdao 266003, China.ORCID https://orcid.org/0000-0001-9767-8173

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

High altitudes pose extreme survival challenges for organisms, yet the origins and molecular strategies underlying their resilience remain poorly understood. Here, we report the molecular and evolutionary mechanisms underlying stress resilience in

Indexed as

ciliateevolutionary genomicsextremophilehigh-altitude adaptation

Identifiers

PMID42130746
PMCPMC13166879

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.