ArticleJournal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques2026
Qualitative phytochemical profiling, antioxidant activity, and development of a water-in-oil cream containing combined oil and water infusions of frankincense resin (
Article in Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Frankincense (gum olibanum, Objectives: The aim of this study was to extract and characterize oil- and water-soluble fractions of frankincense resin, evaluate their antioxidant potential, and incorporate them into a stable water-in-oil ( Methods: Frankincense resin was ground and macerated separately in sweet almond oil and Madinah rosewater to yield oil and water infusions, respectively. Qualitative phytochemical tests and FT-IR spectroscopy were employed for the characterization of both extracts and final formulations. Antioxidant potential was assessed using the DPPH assay followed by the development of a Results: Phytochemical screening showed presence of triterpenoids and boswellic type functionalities predominantly in the oil infusion, whereas saponins and minor alkaloids were detected in the water infusion. In the DPPH assay, significant free radical scavenging activity was observed as sample 2 showed 71% inhibition at 343.46 ± 34.2 μg/mL. The developed cream formulation showed good physical stability, acceptable pH and shear-thinning rheology. Conclusion: A stable, all-natural
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