Evidence map›Paper›PMID 42130372›Full record

SynthesisPeriodontology 20002025

Esthetical and patient-reported outcomes after root coverage procedures for multiple gingival recessions: A systematic review and meta-analysis.

Martina Stefanini, Ilham Mounssif, Elena Figuero, Giovanni Zucchelli, Anton Sculean, Raluca Cosgarea

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in Periodontology 2000, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Martina StefaniniPeriodontal Unit, Department of Biomedical and Neuromotor Sciences, University of Bologna, Bologna, Italy.ORCID https://orcid.org/0000-0002-9154-637X
Ilham MounssifPeriodontal Unit, Department of Biomedical and Neuromotor Sciences, University of Bologna, Bologna, Italy.ORCID https://orcid.org/0000-0001-7663-0402
Elena FigueroEtiology and Therapy of Periodontal and Peri-Implant Diseases (ETEP) Research Group, Department of Dental Clinical Specialties, Faculty of Dentistry, University Complutense of Madrid, Madrid, Spain.
Giovanni ZucchelliDepartment of Periodontology, Dental School of Dental Medicine, University of Bern, Bern, Switzerland.
Anton SculeanDepartment of Periodontology, Dental School of Dental Medicine, University of Bern, Bern, Switzerland.ORCID https://orcid.org/0000-0003-2836-5477
Raluca CosgareaDepartment of Periodontology, Operative and Preventive Dentistry, University of Bonn, Bonn, Germany.ORCID https://orcid.org/0000-0003-2148-9645

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMultiple gingival recessions can lead to esthetic impairments and may require surgical root coverage. Esthetic outcome measures can be assessed from both professional and patient perspectives. Several objective and subjective outcome measures have been applied for these evaluations.

aimTo systematically review and conduct a meta-analysis of the available literature on professional esthetic assessments and patient-related outcome measures (PROMs) following surgical root coverage procedures for the treatment of multiple gingival recessions. MATERIALS AND

methodsA computerized systematic search was conducted in the MEDLINE (via PubMed), EMBASE, and Cochrane Central Register of Controlled Trials databases up to May 2024 to identify eligible studies meeting the inclusion criteria.

resultsA total of 32 randomized controlled trials involving 1012 patients and 3589 multiple gingival recessions were included. No case-series studies meeting the inclusion criteria were retrieved. Meta-analyses demonstrated that root coverage procedures statistically significantly improved both professionally assessed and patient-reported esthetic outcomes. The overall weighted mean Root Coverage Esthetic Score (RES) was 8.31 (95% CI: 8.11-8.50), with comparable results across coronally advanced flap (CAF) and tunnel (TUN) techniques, particularly when combined with autogenous connective tissue grafts or graft substitutes. Patient-reported esthetic satisfaction, measured primarily by visual analog scales (VAS), showed a pooled mean of 8.59 (95% CI: 8.29-8.89). Mean root coverage (MRC) reached 82.6% (95% CI: 71.3-93.9), and complete root coverage (CRC) was 62.7% (95% CI: 57.0-68.4). Statistically significant reductions in recession depth (mean difference = 2.22 mm) and gains in keratinized tissue (0.74 mm), gingival thickness (0.56 mm), and clinical attachment level (2.17 mm) were observed. Postoperative pain was low across techniques (VAS 0-10 mean: 2.67; VAS 0-100 mean: 24.34). Metaregression revealed a positive association between MRC and RES (R

conclusionsThe results of this systematic review and meta-analysis, focusing on multiple gingival recessions, suggest that (a) CAF and TUN with the adjunctive use of autogenous graft support esthetic improvement from both professional and patient perspectives and (b) CAF and TUN with the adjunctive use of autogenous graft or graft substitutes are effective in root coverage outcomes with a minimal postoperative morbidity.

Indexed as

Esthetics, DentalGingival RecessionGingivoplastyPatient Reported Outcome MeasuresTooth RootHumansPatient SatisfactionSurgical FlapsTreatment Outcomeestheticsgingival recessionpatient‐reported outcome measuresperiodontiumsurgical flaps

Identifiers

PMID42130372
PMCPMC13428093

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.