Evidence map›Paper›PMID 42130360›Full record

ArticleZhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics2026

[Fecal microbiota transplantation attenuates gastrointestinal inflammation in murine acute graft-versus-host disease after allogeneic hematopoietic stem cell transplantation by inhibiting RIPK1/RIPK3-mediated necroptosis].

Yue Li, Hao-Shu Niu, Xue-Li Lu, Xue-Chun Li, Min Xiao, Ying Wang, Shao-Jing Yang, Yu-Yu Guo, Yan Sun

Abstract readEnglish Abstract
In one paragraph

Article in Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yue LiDepartment of Pediatrics, The Third Clinical Medical College of Inner Mongolia Medical University, Baotou, Inner Mongolia 014010, China.
Hao-Shu Niu
Xue-Li LuDepartment of Pediatrics, The Third Clinical Medical College of Inner Mongolia Medical University, Baotou, Inner Mongolia 014010, China.
Xue-Chun LiDepartment of Pediatrics, The Third Clinical Medical College of Inner Mongolia Medical University, Baotou, Inner Mongolia 014010, China.
Min XiaoDepartment of Pediatrics, The Third Clinical Medical College of Inner Mongolia Medical University, Baotou, Inner Mongolia 014010, China.
Ying WangDepartment of Pediatrics, The Third Clinical Medical College of Inner Mongolia Medical University, Baotou, Inner Mongolia 014010, China.
Shao-Jing YangDepartment of Pediatrics, The Third Clinical Medical College of Inner Mongolia Medical University, Baotou, Inner Mongolia 014010, China.
Yu-Yu GuoDepartment of Pediatrics, The Third Clinical Medical College of Inner Mongolia Medical University, Baotou, Inner Mongolia 014010, China.
Yan SunDepartment of Pediatrics, The Third Clinical Medical College of Inner Mongolia Medical University, Baotou, Inner Mongolia 014010, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo investigate the molecular mechanism by which fecal microbiota transplantation (FMT) alleviates gastrointestinal inflammation after allogeneic hematopoietic stem cell transplantation (allo-HSCT) in murine acute graft-versus-host disease (aGVHD).

methodsA murine aGVHD model after allo-HSCT was established, and BALB/c mice were randomly assigned to blank control, bone marrow transplantation, aGVHD model, and FMT treatment groups (

resultsCompared with the aGVHD model group, the FMT group showed higher relative abundances of

conclusionsFMT may attenuate gastrointestinal inflammation in aGVHD by restoring intestinal microbial balance and inhibiting the RIPK1/RIPK3-mediated necroptosis pathway.

Indexed as

Fecal Microbiota TransplantationGraft vs Host DiseaseHematopoietic Stem Cell TransplantationNecroptosisReceptor-Interacting Protein Serine-Threonine KinasesAcute DiseaseAnimalsMaleMiceMice, Inbred BALB CProtein KinasesTransplantation, HomologousMLKL protein, mouseProtein KinasesReceptor-Interacting Protein Serine-Threonine KinasesRipk1 protein, mouseRipk3 protein, mouseAcute graft-versus-host diseaseFecal microbiota transplantationIntestinal microbiotaMouseRIPK1/RIPK3

Identifiers

PMID42130360
PMCPMC13173470

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.