Evidence map›Paper›PMID 42130153›Full record

ArticleHaemophilia : the official journal of the World Federation of Hemophilia

Activities of Daily Living and Quality of Life After Orthopaedic Surgery for Haemophilic Arthropathy: A Scoping Review.

Makoto Asaeda, Shunsuke Taito, Yuki Nakashima, Daisuke Iwaki, Shigeru Sato, Yosuke Ishii, Naoto Fujita, Junko Fujitani, Yukio Mikami

Abstract readScoping Review
PubMed Full text at PMC Publisher
In one paragraph

Article in Haemophilia : the official journal of the World Federation of Hemophilia. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Makoto AsaedaDepartment of Rehabilitation Medicine, Hiroshima University Hospital, Hiroshima, Japan.
Shunsuke TaitoDivision of Rehabilitation, Department of Clinical Practice and Support, Hiroshima University Hospital, Hiroshima, Japan.
Yuki NakashimaDivision of Rehabilitation, Department of Clinical Practice and Support, Hiroshima University Hospital, Hiroshima, Japan.
Daisuke IwakiDivision of Rehabilitation, Department of Clinical Practice and Support, Hiroshima University Hospital, Hiroshima, Japan.
Shigeru SatoBio-environmental Adaptation Sciences, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan.
Yosuke IshiiBio-environmental Adaptation Sciences, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan.
Naoto FujitaBio-environmental Adaptation Sciences, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan.
Junko FujitaniDepartment of Rehabilitation Medicine, National Center for Global Health and Medicine, Japan Institute for Health Security, Tokyo, Japan.
Yukio MikamiDepartment of Rehabilitation Medicine, Hiroshima University Hospital, Hiroshima, Japan.

Funding

Health and Labour Sciences Research Grants (HLSRG) 24HB2004
6 · The paper itself

Abstract

introductionHaemophilic arthropathy causes chronic pain and disability. While orthopaedic surgery aims to alleviate these, post-surgical activities of daily living (ADL) and quality of life (QOL) outcomes lack systematic review.

aimTo assess ADL and QOL outcomes after orthopaedic surgery for haemophilic arthropathy and identify research gaps.

methodsThis scoping review searched MEDLINE, Embase, CENTRAL, CINAHL, and PEDro for studies reporting ADL or QOL outcomes in patients undergoing lower-limb orthopaedic surgery for haemophilic arthropathy. Data were qualitatively synthesised.

resultsSixteen studies were included, predominantly on total knee arthroplasty (n = 11). The SF-36 was widely used, whereas haemophilia-specific tools were rare. Despite heterogeneous designs, varied follow-ups, and inconsistent mental health results, most studies demonstrated significant post-surgical improvements in physical function and QOL.

conclusionWhile standardised, disease-specific assessments are needed, this review confirms surgery consistently improves ADL and QOL. However, it should be noted that it is well known that, in a disease as rare as haemophilia, it is very difficult to conduct Level I evidence studies on orthopaedic surgery (prospective, double-blind, randomized trials). In fact, this study confirms what was already well known empirically: that orthopaedic surgery is effective in relieving or eliminating joint pain thereby improving the QOL for patients with advanced haemophilic arthropathy who have not responded to non-surgical treatment.

Indexed as

Activities of Daily LivingHemophilia AJoint DiseasesOrthopedic ProceduresQuality of LifeHumansactivities of daily livinghaemophiliahaemophilic arthropathyorthopaedic surgeryquality of lifescoping review

Identifiers

PMID42130153
PMCPMC13378639

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.