Evidence map›Paper›PMID 42130124›Full record

ArticleOrthopaedic surgery2026

Development and Validation of an AI-Integrated System for Automated Fracture Detection and Pedicle Puncture Planning in Lumbar Osteoporotic Vertebral Compression Fractures Based on the Nine-Grid Area Division Method.

Weiyang Zuo, Yu Xie, Hai Meng, Dong Liu, Shuo Yuan, Jipeng Song, Xiaoda Lei, Xingyu Liu, Yafang Zhang, Lei Zang and 3 more

Abstract readValidation StudyMulticenter Study
In one paragraph

Article in Orthopaedic surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

13 authors.

Weiyang ZuoDepartment of Orthopedics, Beijing Friendship Hospital, Capital Medical University, Beijing, China.
Yu XieDepartment of Orthopedics, Beijing Friendship Hospital, Capital Medical University, Beijing, China.
Hai MengDepartment of Orthopedics, Beijing Friendship Hospital, Capital Medical University, Beijing, China.
Dong LiuLongwood Valley Medical Technology Co Ltd, Beijing, China.
Shuo YuanDepartment of Orthopedics, Beijing Chaoyang Hospital, Capital Medical University, Beijing, China.
Jipeng SongDepartment of Spine Surgery, Beijing Shijitan Hospital, Capital Medical University, Beijing, China.
Xiaoda LeiLongwood Valley Medical Technology Co Ltd, Beijing, China.
Xingyu LiuLongwood Valley Medical Technology Co Ltd, Beijing, China.
Yafang ZhangLongwood Valley Medical Technology Co Ltd, Beijing, China.
Lei ZangDepartment of Orthopedics, Beijing Chaoyang Hospital, Capital Medical University, Beijing, China.
Lixiang DingDepartment of Spine Surgery, Beijing Shijitan Hospital, Capital Medical University, Beijing, China.ORCID https://orcid.org/0000-0003-0064-4773
Lingyi ZhangLongwood Valley Medical Technology Co Ltd, Beijing, China.
Qi FeiDepartment of Orthopedics, Beijing Friendship Hospital, Capital Medical University, Beijing, China.

Funding

Beijing Municipal Natural Science Foundation-Haidian Incubation Project L232054Capital Health Research and Development of Special Fund 2024-2-2024Tongzhou District Science and Technology Program of Beijing Municipality WS2024060
6 · The paper itself

Abstract

objectiveThe clinical application of the Nine-grid Area Division Method for pedicle puncture in L-OVCF is limited by high technical thresholds and low efficiency. This study aimed to develop an AI-integrated automated system for L-OVCF diagnosis and pedicle puncture planning by combining the nine-grid method with deep learning, and to validate its diagnostic accuracy, planning consistency, and clinical application efficiency.

methodsA multicenter CT dataset of L-OVCF patients was collected from three hospitals affiliated with Capital Medical University (January 2020-December 2022). A two-stage improved U-Net architecture was constructed for automated lumbar vertebral segmentation, and a 3D ResNet50 network was used for L-OVCF identification. A geometric algorithm was developed to realize automated puncture path planning based on the Nine-grid Area Division Method. The performance of the segmentation and diagnosis modules was evaluated with DSC, AUC, and Hausdorff Distance. 20 cases were randomly selected to compare the consistency of puncture planning between the AI system and senior surgeons' manual planning, and the planning efficiency and resource consumption of the two methods were analyzed.

resultsThe proposed two-stage U-Net achieved an overall DSC of 0.934 for vertebral segmentation, significantly outperforming the single-stage nnU-Net model. The L-OVCF identification model yielded a high degree of accuracy with AUC of 0.918 (95% CI: 0.885-0.925). The automated planning results showed extremely high consistency with manual planning (DSC = 0.958, IoU = 0.921, HD = 486.7 μm), and the planning efficiency was significantly improved with memory consumption within the capacity of standard clinical workstations.

conclusionsThe developed AI-integrated system accurately reproduces the preoperative planning logic of senior surgeons, with high diagnostic accuracy and puncture planning consistency, while markedly improving planning efficiency and reducing the technical threshold of the nine-grid method. It has good clinical translational potential and can provide a reliable auxiliary tool for the precise and minimally invasive treatment of L-OVCF.

Indexed as

Artificial IntelligenceFractures, CompressionLumbar VertebraeOsteoporotic FracturesPuncturesSpinal FracturesDeep LearningHumansIntelligent SystemsTomography, X-Ray Computedartificial intelligencedeep learningintegrated softwarelumbar osteoporotic vertebral compression fracturePVP technic

Identifiers

PMID42130124
PMCPMC13238890

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LicenceCC BY-NC
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.