Evidence map›Paper›PMID 42130077›Full record

ReviewJournal of cosmetic dermatology2026

Non-Surgical Cosmetic Treatment Modalities for Interdental Papilla Reconstruction "Black Triangles": An Evidence-Based Review.

Ayah Elhaj, Bashar Shatta, Sheila Nguyen, Ines Novo Pereira, Haidar Hassan

Abstract readReview
In one paragraph

Review in Journal of cosmetic dermatology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ayah ElhajAcademic Plastic Surgery, Blizard Institute, Faculty of Medicine and Dentistry, Queen Mary University of London, London, UK.
Bashar ShattaAcademic Plastic Surgery, Blizard Institute, Faculty of Medicine and Dentistry, Queen Mary University of London, London, UK.
Sheila NguyenAcademic Plastic Surgery, Blizard Institute, Faculty of Medicine and Dentistry, Queen Mary University of London, London, UK.
Ines Novo PereiraFaculty of Dental Medicine, University of Porto, Porto, Portugal.ORCID https://orcid.org/0000-0001-8806-3863
Haidar HassanAcademic Plastic Surgery, Blizard Institute, Faculty of Medicine and Dentistry, Queen Mary University of London, London, UK.ORCID https://orcid.org/0000-0002-8192-9916

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe interdental papilla plays a vital role in dental and facial aesthetics, as the loss of papilla manifests as unesthetic "black triangles". In recent years, non-surgical approaches such as hyaluronic acid injections, autologous platelet concentrates, laser therapy, and microneedling with vitamin C have emerged as alternatives to technically demanding and unpredictable surgical reconstruction.

aimTo evaluate the effectiveness, patient satisfaction, and safety of cosmetic non-surgical treatment modalities for the correction of black triangles. MATERIALS AND

methodsA comprehensive literature search was conducted using the PubMed, Cochrane Library, Scopus, and Embase databases, from January 2013 to January 2024. All case series, cohort studies, and randomized controlled trials with relevant outcomes were included. The BestBETs methodology was used, and the risk of bias was assessed using the "Quality Assessment Tool for Quantitative Studies."

resultsA total of 19 human studies met the inclusion criteria. Of these, six studies were classified as level II evidence, while the remaining 13 were categorized as level III or level IV evidence. Based on level II evidence, hyaluronic acid injections were effective and safe for correcting the black triangles and improving the smile. Evidence on non-surgical modalities such as autologous platelet concentrates, photobiomodulation therapy, and microneedling with vitamin C remains limited. Based on level II to level IV evidence, these conservative treatments are recommended as clinically effective for filling black triangle spaces, demonstrating high patient satisfaction and minimal adverse events.

conclusionNon-surgical cosmetic treatments offer a promising alternative for reconstructing interdental papilla deficiencies, with benefits including reduced complications and favorable aesthetic outcomes. However, the current evidence remains limited, and findings should be interpreted with caution. Further well-designed, standardized clinical trials are required to establish the effectiveness, long-term stability, and patient-centred outcomes of these interventions.

Indexed as

Cosmetic TechniquesDental PapillaAscorbic AcidEstheticsHumansHyaluronic AcidLaser TherapyPatient SatisfactionPercutaneous Collagen InductionPlatelet-Rich PlasmaTreatment OutcomeAscorbic AcidHyaluronic Acidblack trianglescosmeticdeficiencyinterdental papillanon‐surgicalreconstruction

Identifiers

PMID42130077
PMCPMC13172656

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.