Evidence map›Paper›PMID 42129751›Full record

ArticleBMC nursing2026

Improving nurses' mental health through an online Acceptance and Commitment Therapy intervention: an exploratory pilot study across two healthcare contexts.

Eveline Frey, Yuen Yu Chong, Wai Tong Chien, Andrew T Gloster

Registry-linked trialAbstract read
In one paragraph

Article in BMC nursing, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04821037 (Feasibility and Acceptability of a Virtual ACT-intervention in Nurses Working During the COVID-19 Pandemic), which is not on this map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04821037 naunknown statusnot on this map

Feasibility and Acceptability of a Virtual ACT-intervention in Nurses Working During the COVID-19 Pandemic (Pilot Study)

TypeinterventionalSponsorProf. Dr. Andrew GlosterRan2021 to 2021Enrolled10ConditionsStressArmsACT
3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Eveline FreyFaculty of Psychology, University of Basel, Basel, Switzerland.
Yuen Yu ChongDivision of Medicine, Chinese University of Hong Kong, The Nethersole School of Nursing, Hong Kong, China. conniechong@cuhk.edu.hk.
Wai Tong ChienDivision of Medicine, Chinese University of Hong Kong, The Nethersole School of Nursing, Hong Kong, China.
Andrew T GlosterDivision of Clinical Psychology, University of Lucerne, Lucerne, Switzerland.

Funding

Swiss National Science Foundation SNF Grant # PP00P1_190082Swiss State Secretariat for Education, Research, and Innovation SERI # COV_09_062020
6 · The paper itself

Abstract

backgroundThe COVID-19 pandemic negatively impacted healthcare workers' (HCWs) mental health, particularly nurses, due to their demanding frontline roles. Easily accessible psychological interventions are needed to support their well-being, especially during crises like lockdowns. This study aimed to support nurses during the pandemic through online-based Acceptance and Commitment Therapy (ACT) interventions. While ACT, a third-wave cognitive-behavioral approach, has shown effectiveness in reducing work-related stress, its impact on nurses across cultures remains unexplored.

methodsWe used a multi-stage process (Delphi Method) to develop online-based ACT interventions. This process included a needs assessment through semi-structured interviews with nurses (Hong Kong: n = 8; Switzerland: n = 20) and focus groups conducted to evaluate the interventions before implementation. The intervention - consisting of two half-day workshops - was then tested in a pilot study with nurses from Hong Kong (n = 7) and Switzerland (n = 10).

resultsLevels of stress, emotional exhaustion, anxiety, and depression decreased, while levels of psychological flexibility increased over time. No regional interaction effects were observed, except for depression, which declined more significantly among Hong Kong nurses than Swiss nurses.

conclusionsThis was the first study to examine an online ACT intervention for nurses across different cultural backgrounds. Findings suggest ACT effectively improves nurses' mental health, but further research is needed to confirm its effectiveness in varied settings due to the study's exploratory design and limited sample size.

trial registrationThe study was prospectively registered at ClinicalTrials.gov on 10.03.2021 (ID: NCT04821037), prior to data collection. In addition, the study was retrospectively registered with the Open Science Framework (OSF; registration number tpgd6) on 12.06.2025 to provide additional documentation and materials.

Indexed as

Acceptance and commitment therapyCOVID-19 pandemicDigital psychological interventionsHealthcare contextsNursing professionalsPsychological flexibility

Identifiers

PMID42129751
PMCPMC13352774

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.