Evidence map›Paper›PMID 42129749›Full record

SynthesisBMC medical informatics and decision making2026

Artificial intelligence models in cerebral infarction: performance and applications in diagnosis, classification, grading, treatment, and disease course prediction-a systematic review.

Lingyun Xiang, Yiyu Fang, Zhanzhan

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in BMC medical informatics and decision making, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Lingyun XiangCiXi Health Continuing Education School, Ningbo, 315399, China. 15858470362@163.com.
Yiyu FangCixi People's Hospital Medical and Health Group, Ningbo, 315300, China.
ZhanzhanCixi People's Hospital Medical and Health Group, Ningbo, 315300, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Artificial intelligence (AI) holds significant promise for transforming cerebral infarction care, yet its real-world performance across the entire disease management continuum remains inadequately synthesized, with heterogeneous evidence and unclear clinical translation pathways. To address this gap, this systematic review and meta-analysis comprehensively evaluates the performance and application value of AI models in diagnosis, subtype classification, severity grading, treatment guidance, and prognosis prediction for cerebral infarction. Adhering to PRISMA 2020 guidelines, we identified 76 eligible studies (n = 45,289 patients) published between 2015 and 2025. Pooled estimates were derived using bivariate random-effects meta-analysis for diagnostic accuracy and random-effects models with restricted maximum-likelihood estimation for other outcomes. AI models demonstrated robust diagnostic accuracy (pooled sensitivity: 0.92, specificity: 0.89, AUC: 0.95), and consistently high performance in classification (accuracy: 0.87), grading (AUC: 0.91), treatment response prediction (AUC: 0.88), and 3-month functional outcome prediction (AUC: 0.90). Substantial heterogeneity was observed across diagnostic studies (I

Indexed as

Artificial IntelligenceCerebral InfarctionHumansPredictive Learning ModelsPrognosisArtificial intelligenceClinical decision supportIschemic strokePredictive modelingSystematic review

Identifiers

PMID42129749
PMCPMC13340257

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.