Evidence map›Paper›PMID 42129736›Full record

ArticleBMC surgery2026

Risk factors for acute kidney injury after nephron-sparing surgery in sporadic renal angiomyolipoma: a multicenter retrospective cohort study.

Yuezhang Wu, Yongkang Zhai, Jiale Sun, Qiang Liu, Qi Cao, Run Tao, Jingqiang Chen, Wenliang Xie, Ming Li, Tao Zhang

Abstract readMulticenter Study
In one paragraph

Article in BMC surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Yuezhang Wu *Department of Urology, the Second Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.
Yongkang Zhai *Department of Urology, Anhui Provincial Hospital, Hefei, Anhui, China.
Jiale Sun *Department of Urology, the First Affiliated Hospital of Bengbu Medical University, Bengbu, Anhui, China.
Qiang Liu *Department of Urology, the Second Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.
Qi CaoDepartment of Urology, Jieshou People's Hospital, Jieshou, Anhui, China.
Run TaoDepartment of Urology, Lu 'an People's Hospital, Lu 'an, Anhui, China.
Jingqiang ChenDepartment of Urology, The First Affiliated Hospital of Anhui University of Science and Technology, South District, Huainan, Anhui, China.
Wenliang XieDepartment of Urology, Fuyang People's Hospital, Fuyang, Anhui, China.
Ming LiDepartment of Urology, Fuyang People's Hospital, Fuyang, Anhui, China.
Tao ZhangDepartment of Urology, the Second Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China. zhangtao@ahmu.edu.cn.

Funding

Anhui Medical University 2021xkjT036Anhui Provincial Natural Science Foundation 2008085MH290the Major Project of Natural Science Research in Universities of Anhui Province 2024AH040106the Second Affiliated Hospital of Anhui Medical University 2024AH040108
6 · The paper itself

Abstract

backgroundAcute kidney injury (AKI) is a significant complication following nephron-sparing surgery (NSS) for renal angiomyolipoma (RAML). Identifying risk factors is crucial for perioperative management. This study aimed to investigate the independent risk factors for AKI following NSS in patients with sporadic RAML.

methodsA multicenter retrospective cohort study was conducted involving 413 patients who underwent NSS for sporadic RAML between January 2012 and December 2024 at seven tertiary urology centers. Patients were categorized into AKI and non-AKI groups based on KDIGO 2012 criteria. Univariate analysis and multivariate logistic regression were used to identify risk factors associated with postoperative AKI.

resultsAmong 413 patients, 65 (15.7%) developed postoperative AKI. Multivariate analysis identified four independent risk factors: elevated preoperative blood urea nitrogen (BUN) (OR = 1.30, 95% CI 1.09-1.55), higher RENAL nephrometry score (OR = 1.32, 95% CI 1.06-1.65), longer operative time (per 30-min increase: OR = 1.32, 95% CI 1.12-1.57), and prolonged renal artery occlusion time (OR = 1.09, 95% CI 1.04-1.15). The combined predictive model incorporating these four factors achieved a high specificity of 92.0% for AKI prediction, with favorable discriminative performance.

conclusionsPreoperative BUN level, RENAL score, operative time, and renal artery occlusion time are independent risk factors for AKI after NSS in sporadic RAML patients. These findings support enhanced preoperative assessment and targeted intraoperative strategies, such as minimizing ischemia time, to reduce AKI risk.

Indexed as

Acute Kidney InjuryAngiomyolipomaKidney NeoplasmsNephrectomyOrgan Sparing TreatmentsPostoperative ComplicationsAdultFemaleHumansMaleMiddle AgedNephronsRetrospective StudiesRisk FactorsAcute kidney injuryNephron-sparing surgeryRisk factorsSporadic renal angiomyolipoma

Identifiers

PMID42129736
PMCPMC13343940

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.