Evidence map›Paper›PMID 42129707›Full record

ArticleBMC musculoskeletal disorders2026

Spatial gradient in vertebral-disc coupling: independent associations of bone marrow fat fraction and perfusion with disc biochemistry.

Changyan Liu, Yuting Zhou, Xiangwen Li, Haoyu Liang, Yuxue Xie, Yiwen Hu, Qing Li, Hongyue Tao, Shuang Chen

Abstract read
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Article in BMC musculoskeletal disorders, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Changyan Liu *Department of Radiology and Institute of Medical Functional and Molecular Imaging, Huashan Hospital, Fudan University, 12 Wulumuqizhong Road, Shanghai, 200040, China.
Yuting Zhou *Department of Radiology and Institute of Medical Functional and Molecular Imaging, Huashan Hospital, Fudan University, 12 Wulumuqizhong Road, Shanghai, 200040, China.
Xiangwen LiDepartment of Radiology and Institute of Medical Functional and Molecular Imaging, Huashan Hospital, Fudan University, 12 Wulumuqizhong Road, Shanghai, 200040, China.
Haoyu LiangDepartment of Radiology and Institute of Medical Functional and Molecular Imaging, Huashan Hospital, Fudan University, 12 Wulumuqizhong Road, Shanghai, 200040, China.
Yuxue XieDepartment of Radiology and Institute of Medical Functional and Molecular Imaging, Huashan Hospital, Fudan University, 12 Wulumuqizhong Road, Shanghai, 200040, China.
Yiwen HuDepartment of Radiology and Institute of Medical Functional and Molecular Imaging, Huashan Hospital, Fudan University, 12 Wulumuqizhong Road, Shanghai, 200040, China.
Qing LiMR Collaborations, Siemens Healthineers Ltd., Shanghai, China.
Hongyue TaoDepartment of Radiology and Institute of Medical Functional and Molecular Imaging, Huashan Hospital, Fudan University, 12 Wulumuqizhong Road, Shanghai, 200040, China.
Shuang ChenDepartment of Radiology and Institute of Medical Functional and Molecular Imaging, Huashan Hospital, Fudan University, 12 Wulumuqizhong Road, Shanghai, 200040, China. chenshuang6898@126.com.

Funding

National Natural Science Foundation of China No. 82271968
6 · The paper itself

Abstract

purposeTo evaluate the relationship between vertebral bone marrow fat, blood flow perfusion, and IVD biochemical components in postmenopausal women using quantitative MRI. MATERIALS AND

methodsPostmenopausal women were categorized into three groups based on QCT: normal BMD (n = 34), osteopenia (n = 27), and osteoporosis (n = 24). Lumbar vertebral bone marrow fat fraction (FF) was quantified using a 6-echo-based Dixon sequence. Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) provided quantitative parameters for bone marrow blood perfusion (K

resultsSignificant differences were found in FF, K

conclusionBoth vertebral bone marrow FF and K

Indexed as

Adipose TissueBone MarrowIntervertebral DiscIntervertebral Disc DegenerationLumbar VertebraeAgedDynamic Contrast Enhanced Magnetic Resonance ImagingFemaleHumansMagnetic Resonance ImagingMiddle AgedPostmenopauseBone marrow fatDixonIntervertebral disc degenerationOsteoporosisT2 mapping

Identifiers

PMID42129707
PMCPMC13343799

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.