Evidence map›Paper›PMID 42129648›Full record

ArticleBMC gastroenterology2026

CT semantic features of primary gastric cancer: a preoperative predictive model for peritoneal metastasis with superior efficacy to conventional direct CT assessment.

Shuxiang Chen, Huijuan Zhang, Yifan Chen, Shuo Chen

Abstract read
In one paragraph

Article in BMC gastroenterology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Shuxiang ChenDepartment of Radiology, Shengli Clinical Medical College of Fujian Medical University, Fujian Provincial Hospital, Fuzhou University Affiliated Provincial Hospital, Fuzhou, Fujian, 350001, China. 0616@fzu.edu.cn.ORCID http://orcid.org/0000-0003-2062-2563
Huijuan ZhangDepartment of Radiology, Shengli Clinical Medical College of Fujian Medical University, Fujian Provincial Hospital, Fuzhou University Affiliated Provincial Hospital, Fuzhou, Fujian, 350001, China.
Yifan ChenDepartment of Breast Surgery, Shengli Clinical Medical College of Fujian Medical University, Fujian Provincial Hospital, Fuzhou University Affiliated Provincial Hospital, Fuzhou, Fujian, 350001, China.
Shuo ChenDepartment of Obstetrics and gynecology, Shengli Clinical Medical College of Fujian Medical University, Fujian Provincial Hospital, Fuzhou University Affiliated Provincial Hospital, Fuzhou, Fujian, 350001, China.

Funding

Joint Funds for the Innovation of Science and Technology of Fujian Province 2024Y9040Startup Fund for Scientific Research of Fujian Medical University 2018QH1138
6 · The paper itself

Abstract

objectivesThis study aims to evaluate the utility of CT semantic features of primary Gastric Cancer(GC) compared to conventional CT assessments for predicting Peritoneal Metastasis(PM) , and to construct a preoperative predictive model.

methodsWe conducted a retrospective analysis involving 257 pathologically confirmed GC patients (92 with PM and 165 without PM), utilizing preoperative contrast-enhanced abdominal CT alongside clinicopathological data. Univariate and multivariate logistic regression analyses were performed to identify risk factors for PM, leading to the development of three predictive models: one based on primary tumor CT signs, another on peritoneal CT signs, and a combined model integrating both sets of features.

resultsIndependent PM predictors included the primary tumor's maximum size, serosal invasion, thickness, enhancement, and the presence of ascites. The primary tumor model demonstrated superior performance (AUC=0.920) compared to the peritoneal model (AUC=0.822, p<0.001). No significant difference was observed between the primary tumor model and the combined model (AUC=0.936, p=0.178). The combined model exhibited the highest sensitivity at 75.0%, while all models maintained a specificity of 98.2%.

conclusionsCT semantic features of primary GC and ascites are effective in predicting PM. The primary tumor-based model surpasses conventional CT in performance, and the combined model further enhances sensitivity. This methodology improves preoperative PM assessment, may help reduce the incidence of non-therapeutic surgeries, and contributes positively to the prognosis of GC patients.

Indexed as

Peritoneal NeoplasmsStomach NeoplasmsTomography, X-Ray ComputedAdultAgedAscitesContrast MediaFemaleHumansLogistic ModelsMaleMiddle AgedNeoplasm InvasivenessPredictive Value of TestsRetrospective StudiesRisk FactorsContrast MediaComputed tomographyGastric cancerPeritoneal metastasisX-ray

Identifiers

PMID42129648
PMCPMC13224590

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LicenceCC BY-NC-ND
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.