Evidence map›Paper›PMID 42129628›Full record

ArticleBMC anesthesiology2026

A postoperative dynamic nomogram for predicting myocardial injury after noncardiac surgery in high-risk patients undergoing laparoscopic colorectal cancer resection.

Yuanqiang Li, Wenting Jiang, Jingchen Liu

Abstract read
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Article in BMC anesthesiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

3 authors.

Yuanqiang Li *Department of Anesthesiology, Nanxishan Hospital of Guangxi Zhuang Autonomous Region (The Second Peoples Hospital of Guangxi Zhuang Autonomous Region), Guilin, Guangxi, 541002, China.ORCID http://orcid.org/0000-0001-8497-8978
Wenting Jiang *School of Nursing, Guangxi University of Chinese Medicine, Nanning, Guangxi, 530200, China.ORCID http://orcid.org/0000-0001-5260-6360
Jingchen LiuDepartment of Anesthesiology, The First Affiliated Hospital of Guangxi Medical University, 6 Shuangyong Road, Nanning, Guangxi, 530021, China. jingchenl2021@163.com.ORCID http://orcid.org/0000-0002-5811-2158

Funding

The Guangxi Appropriate Health Technology Development and Promotion Project S2021058The Guilin Science and Technology Plan Project 20220139-13-1
6 · The paper itself

Abstract

backgroundMyocardial injury after noncardiac surgery (MINS) is closely associated with perioperative cardiovascular events and is a critical complication leading to poor prognosis. This study aimed to develop a nomogram model to predict the risk of MINS in high-risk patients undergoing colorectal cancer surgery, which can be applied immediately after surgery to guide postoperative troponin monitoring and individualized intervention.

methodsThis study retrospectively included 358 patients at high cardiovascular risk who underwent laparoscopic colorectal cancer surgery from August 2021 to January 2023. They were assigned randomly to training and validation cohorts in a 7:3 ratio. After univariate analysis and multicollinearity assessment, multivariable logistic regression identified independent predictors associated with MINS in the training cohort, and nomogram prediction models were constructed. The nomogram model's discrimination, calibration, and clinical validity in the training and validation cohorts were evaluated and validated.

resultsAge, preoperative hemoglobin, preoperative high-sensitivity troponin T (hs‑cTnT), and the Surgical Apgar Score (SAS) were identified as independent predictors. The AUC (C‑index) of the nomogram constructed from these four predictors was 0.884 (95% CI: 0.831-0.937) and 0.853 (95% CI: 0.729-0.977) in the training and validation cohorts, respectively. Decision curve analysis indicated favorable clinical utility, with a positive net benefit across a wide range of threshold probabilities including the recommended 20% risk threshold.

conclusionA postoperative dynamic nomogram based on preoperative and intraoperative variables provides a simple, practical tool for predicting MINS risk in high-risk patients undergoing colorectal cancer surgery. The model showed favorable discriminative ability and calibration upon internal validation, but prospective external validation is needed before clinical implementation.

trial registrationThe study was registered with the Chinese Clinical Trial Registry (ChiCTR2200065961, 20/11/2022).

Indexed as

Colorectal NeoplasmsHeart InjuriesLaparoscopyNomogramsPostoperative ComplicationsAgedColorectal Surgical ProceduresFemaleHumansMaleMiddle AgedPredictive Value of TestsRetrospective StudiesRisk FactorsTroponin TTroponin TColorectal cancer surgeryDynamic nomogramHigh-risk patientsMyocardial injury after noncardiac surgeryPostoperative risk stratification

Identifiers

PMID42129628
PMCPMC13339509

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.